KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
3.64
Human Site:
T2453
Identified Species:
8
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
T2453
A
T
G
R
S
P
R
T
P
R
A
S
G
P
A
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S2733
E
E
A
V
A
T
N
S
G
R
S
S
R
T
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
W2329
I
S
C
P
V
K
G
W
R
W
L
A
S
P
W
Dog
Lupus familis
XP_537779
2046
229120
S1995
E
E
A
V
A
T
N
S
G
R
S
S
R
T
S
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
P2316
G
G
A
H
D
P
A
P
R
S
P
R
T
P
R
Rat
Rattus norvegicus
P54282
2212
251509
P2161
P
K
D
R
K
H
R
P
H
H
H
H
H
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
N2139
A
S
N
L
L
N
G
N
I
S
N
G
T
N
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
Q2250
P
E
P
A
E
S
G
Q
A
H
P
R
R
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1800
D
R
E
R
E
V
E
R
E
R
L
E
Y
I
A
Honey Bee
Apis mellifera
NP_001159376
1904
215872
Q1853
G
Q
H
L
P
P
M
Q
P
S
H
C
P
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
G1915
M
P
N
G
F
R
P
G
G
V
E
K
G
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
13.3
6.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
40
20
40
N.A.
13.3
13.3
N.A.
N.A.
13.3
N.A.
0
N.A.
20
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
28
10
19
0
10
0
10
0
10
10
0
0
19
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
28
10
0
19
0
10
0
10
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
10
0
0
28
10
28
0
0
10
19
0
19
% G
% His:
0
0
10
10
0
10
0
0
10
19
19
10
10
10
10
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
10
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
19
10
0
0
0
0
0
19
0
0
10
0
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
19
0
0
10
19
10
0
0
10
0
0
10
0
% N
% Pro:
19
10
10
10
10
28
10
19
19
0
19
0
10
28
10
% P
% Gln:
0
10
0
0
0
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
28
0
10
19
10
19
37
0
19
28
10
10
% R
% Ser:
0
19
0
0
10
10
0
19
0
28
19
28
10
0
28
% S
% Thr:
0
10
0
0
0
19
0
10
0
0
0
0
19
19
0
% T
% Val:
0
0
0
19
10
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _