KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
9.7
Human Site:
Y1221
Identified Species:
21.33
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
Y1221
G
P
K
P
M
P
P
Y
S
S
M
F
I
L
S
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1571
G
P
R
P
I
V
P
Y
S
S
M
F
C
L
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
H1127
T
G
K
A
M
V
P
H
S
S
M
F
I
F
S
Dog
Lupus familis
XP_537779
2046
229120
Y858
H
Y
I
V
T
M
R
Y
F
E
M
V
I
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
Y1172
G
P
K
P
M
P
P
Y
S
S
M
F
I
L
S
Rat
Rattus norvegicus
P54282
2212
251509
D1024
L
P
L
A
E
D
L
D
N
M
K
N
N
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
K1002
S
S
A
I
S
V
V
K
I
L
R
V
L
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
I1106
P
P
Y
T
S
M
F
I
L
T
T
T
N
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
L663
Y
T
L
L
N
V
F
L
A
I
A
V
D
N
L
Honey Bee
Apis mellifera
NP_001159376
1904
215872
F716
A
L
L
G
M
Q
L
F
G
G
Q
F
N
F
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
I778
V
P
Y
S
A
L
F
I
F
S
T
T
N
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
73.3
60
26.6
N.A.
100
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
86.6
66.6
26.6
N.A.
100
13.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
28
10
19
0
0
46
0
19
10
% F
% Gly:
28
10
0
10
0
0
0
0
10
10
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
19
10
10
0
0
37
0
0
% I
% Lys:
0
0
28
0
0
0
0
10
0
0
10
0
0
10
0
% K
% Leu:
10
10
28
10
0
10
19
10
10
10
0
0
10
37
19
% L
% Met:
0
0
0
0
37
19
0
0
0
10
46
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
10
37
10
0
% N
% Pro:
10
55
0
28
0
19
37
0
0
0
0
0
0
19
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
10
0
0
10
0
% R
% Ser:
10
10
0
10
19
0
0
0
37
46
0
0
0
0
37
% S
% Thr:
10
10
0
10
10
0
0
0
0
10
19
19
0
0
0
% T
% Val:
10
0
0
10
0
37
10
0
0
0
0
28
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
19
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _