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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1A All Species: 4.24
Human Site: Y1483 Identified Species: 9.33
UniProt: O00555 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00555 NP_001120693.1 2505 282365 Y1483 N Q G P S P G Y R M E M S I F
Chimpanzee Pan troglodytes XP_520396 2784 310342 Y1836 E Q G P S P G Y R M E L S I F
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 N1392 D R G P S R S N R M E M S I F
Dog Lupus familis XP_537779 2046 229120 R1100 Q G P S P G Y R M E L S I F Y
Cat Felis silvestris
Mouse Mus musculus P97445 2368 267629 Q1415 S T G E G W P Q V L K H S V D
Rat Rattus norvegicus P54282 2212 251509 I1266 Y F R D L W N I L D F I V V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 A1244 M L N T L C L A M Q H Y G Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690548 2303 262065 A1353 V L K H S V D A T Y E N Q G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 V905 V N S L K N V V N I L I V Y I
Honey Bee Apis mellifera NP_001159376 1904 215872 P958 D L G I I L H P G S Y L R E F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 D1020 S T G E G W P D V L K H S I E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55 55.9 54.6 N.A. 87.9 82.7 N.A. N.A. 35.9 N.A. 72.3 N.A. 43 44.4 N.A. 39.6
Protein Similarity: 100 63.5 66.3 63.4 N.A. 89.9 84.6 N.A. N.A. 50.4 N.A. 80 N.A. 53.9 55.4 N.A. 51.6
P-Site Identity: 100 86.6 66.6 0 N.A. 13.3 0 N.A. N.A. 0 N.A. 13.3 N.A. 0 13.3 N.A. 20
P-Site Similarity: 100 93.3 80 6.6 N.A. 40 13.3 N.A. N.A. 0 N.A. 13.3 N.A. 13.3 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 10 0 0 10 10 0 10 0 0 0 0 10 % D
% Glu: 10 0 0 19 0 0 0 0 0 10 37 0 0 10 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 10 0 0 10 37 % F
% Gly: 0 10 55 0 19 10 19 0 10 0 0 0 10 10 0 % G
% His: 0 0 0 10 0 0 10 0 0 0 10 19 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 10 0 10 0 19 10 37 10 % I
% Lys: 0 0 10 0 10 0 0 0 0 0 19 0 0 0 0 % K
% Leu: 0 28 0 10 19 10 10 0 10 19 19 19 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 19 28 0 19 0 0 0 % M
% Asn: 10 10 10 0 0 10 10 10 10 0 0 10 0 0 0 % N
% Pro: 0 0 10 28 10 19 19 10 0 0 0 0 0 0 10 % P
% Gln: 10 19 0 0 0 0 0 10 0 10 0 0 10 10 0 % Q
% Arg: 0 10 10 0 0 10 0 10 28 0 0 0 10 0 0 % R
% Ser: 19 0 10 10 37 0 10 0 0 10 0 10 46 0 19 % S
% Thr: 0 19 0 10 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 19 0 0 0 0 10 10 10 19 0 0 0 19 19 0 % V
% Trp: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 19 0 10 10 10 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _