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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITPNM1
All Species:
18.79
Human Site:
Y957
Identified Species:
45.93
UniProt:
O00562
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00562
NP_001124320.1
1244
134848
Y957
T
G
E
K
V
D
V
Y
I
M
T
Q
P
L
S
Chimpanzee
Pan troglodytes
XP_511990
1210
132338
L909
T
G
E
K
V
D
I
L
V
M
A
E
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001117918
1332
143014
Y1045
T
G
E
K
V
D
V
Y
I
M
T
Q
P
L
S
Dog
Lupus familis
XP_851829
1245
134601
Y958
T
G
E
K
V
D
V
Y
I
M
T
Q
P
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O35954
1243
134921
Y956
T
G
E
K
V
D
V
Y
V
M
T
Q
P
L
S
Rat
Rattus norvegicus
Q5U2N3
1242
134965
Y955
T
G
E
K
V
D
V
Y
V
M
T
Q
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415122
1326
147711
L1012
G
P
L
D
M
V
T
L
T
G
E
K
V
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691794
898
98981
T617
T
N
S
S
G
R
V
T
Y
T
I
P
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P43125
1259
138877
E965
A
N
D
V
I
V
Q
E
G
R
E
Q
R
L
N
Honey Bee
Apis mellifera
XP_393355
1213
135750
W912
P
G
Q
P
R
E
K
W
N
K
K
R
T
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
90.3
95
N.A.
93.3
93.4
N.A.
N.A.
53.7
N.A.
36.6
N.A.
40.3
40.8
N.A.
N.A.
Protein Similarity:
100
55
91.5
96.4
N.A.
95.5
95.5
N.A.
N.A.
68.3
N.A.
48.5
N.A.
57.6
56.7
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
13.3
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
13.3
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
60
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
60
0
0
10
0
10
0
0
20
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
70
0
0
10
0
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
30
0
10
0
0
0
10
% I
% Lys:
0
0
0
60
0
0
10
0
0
10
10
10
10
0
10
% K
% Leu:
0
0
10
0
0
0
0
20
0
0
0
0
0
60
0
% L
% Met:
0
0
0
0
10
0
0
0
0
60
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
10
10
0
10
0
0
0
0
0
0
0
10
60
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
60
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
0
10
0
10
10
0
0
% R
% Ser:
0
0
10
10
0
0
0
0
0
0
0
0
0
30
60
% S
% Thr:
70
0
0
0
0
0
10
10
10
10
50
0
10
0
0
% T
% Val:
0
0
0
10
60
20
60
0
30
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _