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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
19.7
Human Site:
S275
Identified Species:
33.33
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
S275
D
F
F
D
P
V
E
S
D
E
D
I
T
N
V
Chimpanzee
Pan troglodytes
XP_515539
681
78871
S275
D
F
F
D
P
V
E
S
D
E
D
I
T
N
V
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
S276
D
F
F
D
P
V
E
S
D
E
D
T
T
S
V
Dog
Lupus familis
XP_849351
676
78277
S274
D
F
F
D
P
V
E
S
D
E
D
L
A
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
S277
D
F
F
D
P
V
E
S
D
E
D
I
T
G
V
Rat
Rattus norvegicus
NP_001099810
676
77809
P274
K
Y
K
D
F
F
D
P
V
E
S
D
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
G104
R
R
A
T
W
S
K
G
R
G
H
A
E
R
A
Chicken
Gallus gallus
XP_413769
665
76446
D258
S
R
D
L
T
Y
K
D
F
F
D
P
V
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
G276
D
F
F
A
P
V
D
G
E
P
D
P
I
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
S259
D
F
F
N
E
N
E
S
E
N
E
N
E
P
D
Honey Bee
Apis mellifera
XP_394707
639
74546
E248
N
D
E
E
E
L
E
E
N
E
L
D
D
N
E
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
A251
F
G
S
R
E
T
V
A
E
T
E
K
M
N
G
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
A271
D
F
F
A
A
P
G
A
E
M
A
T
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
D225
F
Q
D
M
P
S
D
D
E
E
E
E
A
I
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
86.6
80
N.A.
93.3
13.3
N.A.
0
6.6
N.A.
40
N.A.
33.3
20
6.6
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
33.3
N.A.
6.6
20
N.A.
53.3
N.A.
53.3
46.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
8
0
0
15
0
0
8
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
58
8
15
43
0
0
22
15
36
0
50
15
8
8
22
% D
% Glu:
0
0
8
8
22
0
50
8
36
58
22
8
22
8
8
% E
% Phe:
15
58
58
0
8
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
15
0
8
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
22
8
8
0
% I
% Lys:
8
0
8
0
0
0
15
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
8
% M
% Asn:
8
0
0
8
0
8
0
0
8
8
0
8
0
29
0
% N
% Pro:
0
0
0
0
50
8
0
8
0
8
0
15
0
15
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
15
0
8
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
8
0
8
0
0
15
0
43
0
0
8
0
0
22
8
% S
% Thr:
0
0
0
8
8
8
0
0
0
8
0
15
29
0
0
% T
% Val:
0
0
0
0
0
43
8
0
8
0
0
0
8
0
36
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _