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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
13.64
Human Site:
S289
Identified Species:
23.08
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
S289
V
H
D
D
E
L
D
S
N
K
E
D
D
E
I
Chimpanzee
Pan troglodytes
XP_515539
681
78871
S289
V
H
D
D
E
L
D
S
N
K
E
D
D
E
I
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
S290
V
H
D
D
E
L
D
S
N
K
D
D
D
E
I
Dog
Lupus familis
XP_849351
676
78277
N288
V
H
D
E
L
G
S
N
E
E
E
E
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
D291
V
D
E
E
L
G
P
D
E
E
K
E
E
E
E
Rat
Rattus norvegicus
NP_001099810
676
77809
L288
M
T
G
V
E
G
E
L
G
S
D
E
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
G118
A
R
F
I
G
A
R
G
G
D
E
E
E
I
Q
Chicken
Gallus gallus
XP_413769
665
76446
N272
D
N
D
D
L
V
A
N
D
A
E
D
Y
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
S290
D
E
E
K
E
L
E
S
N
D
D
Y
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
E273
D
E
D
A
N
P
K
E
G
D
S
D
Q
S
E
Honey Bee
Apis mellifera
XP_394707
639
74546
S262
E
L
L
E
S
L
D
S
D
S
N
N
E
I
D
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
K265
G
E
K
K
K
I
E
K
D
K
K
R
K
A
G
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
E285
S
K
K
K
V
H
F
E
G
G
E
E
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
K239
Y
Y
E
D
F
F
D
K
P
T
K
E
P
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
93.3
26.6
N.A.
13.3
13.3
N.A.
6.6
33.3
N.A.
26.6
N.A.
13.3
20
6.6
13.3
P-Site Similarity:
100
100
100
60
N.A.
53.3
46.6
N.A.
20
60
N.A.
53.3
N.A.
13.3
46.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
0
0
8
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
8
43
36
0
0
36
8
22
22
22
36
22
0
15
% D
% Glu:
8
22
22
22
36
0
22
15
15
15
43
43
50
50
29
% E
% Phe:
0
0
8
0
8
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
8
22
0
8
29
8
0
0
0
8
15
% G
% His:
0
29
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
0
0
22
22
% I
% Lys:
0
8
15
22
8
0
8
15
0
29
22
0
8
0
8
% K
% Leu:
0
8
8
0
22
36
0
8
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
15
29
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
0
0
8
0
8
36
0
15
8
0
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
36
0
0
8
8
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _