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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
14.85
Human Site:
S305
Identified Species:
25.13
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
S305
E
E
E
A
E
E
L
S
I
S
E
T
D
E
D
Chimpanzee
Pan troglodytes
XP_515539
681
78871
S305
E
E
A
A
E
E
L
S
I
S
E
T
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
N306
E
E
E
A
E
E
L
N
I
S
E
T
D
E
D
Dog
Lupus familis
XP_849351
676
78277
E303
D
E
E
E
S
I
S
E
M
D
E
D
N
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
S307
F
A
E
E
A
D
E
S
I
S
D
T
D
E
D
Rat
Rattus norvegicus
NP_001099810
676
77809
S303
L
P
E
E
A
A
D
S
M
S
E
S
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
H133
G
N
K
D
K
K
Q
H
R
E
A
L
K
R
V
Chicken
Gallus gallus
XP_413769
665
76446
N290
D
S
A
I
E
K
E
N
E
E
S
M
S
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
Y308
D
D
E
L
E
E
E
Y
E
E
D
M
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
P288
G
D
E
G
D
D
E
P
E
N
D
Q
D
P
D
Honey Bee
Apis mellifera
XP_394707
639
74546
S278
D
N
E
M
E
E
K
S
S
S
K
K
K
V
T
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
G282
A
D
L
S
L
D
D
G
K
N
K
K
R
V
R
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
A310
E
E
E
S
F
E
E
A
D
F
E
D
A
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
P254
K
H
S
D
V
K
D
P
K
E
D
E
E
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
93.3
93.3
20
N.A.
53.3
46.6
N.A.
0
13.3
N.A.
26.6
N.A.
20
33.3
0
40
P-Site Similarity:
100
93.3
100
46.6
N.A.
66.6
60
N.A.
20
33.3
N.A.
60
N.A.
53.3
46.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
22
15
8
0
8
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
22
0
15
8
22
22
0
8
8
29
15
43
15
58
% D
% Glu:
29
36
65
22
43
43
36
8
22
29
43
8
8
50
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
15
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
29
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
8
22
8
0
15
0
15
15
15
0
0
% K
% Leu:
8
0
8
8
8
0
22
0
0
0
0
8
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
15
0
0
15
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
15
0
15
0
0
15
0
0
% N
% Pro:
0
8
0
0
0
0
0
15
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
8
% R
% Ser:
0
8
8
15
8
0
8
36
8
43
8
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _