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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
22.42
Human Site:
S353
Identified Species:
37.95
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
S353
V
L
N
V
K
K
N
S
D
E
V
K
S
S
F
Chimpanzee
Pan troglodytes
XP_515539
681
78871
S353
V
L
N
V
K
K
N
S
D
E
V
K
S
S
F
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
S354
V
L
N
V
K
K
N
S
D
E
V
K
S
S
F
Dog
Lupus familis
XP_849351
676
78277
S348
I
L
N
V
Q
K
D
S
D
D
V
K
S
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
S354
P
L
A
V
K
Q
E
S
D
E
V
K
S
S
F
Rat
Rattus norvegicus
NP_001099810
676
77809
S349
S
L
A
V
K
Q
E
S
D
E
V
K
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
P178
E
A
K
I
S
P
S
P
A
P
P
Y
H
C
M
Chicken
Gallus gallus
XP_413769
665
76446
L337
Q
L
E
R
G
I
D
L
N
E
T
K
S
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
K359
D
I
L
G
G
K
A
K
D
V
P
K
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
E333
E
E
E
P
Q
P
T
E
P
P
S
Q
S
S
N
Honey Bee
Apis mellifera
XP_394707
639
74546
K323
E
M
R
Q
E
R
L
K
N
K
I
G
K
L
E
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
E329
L
L
G
A
D
L
E
E
P
K
E
E
S
A
F
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
K358
L
G
G
G
Q
R
K
K
G
E
D
K
S
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
S299
A
S
D
K
N
L
S
S
F
E
K
Q
Q
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
0
40
N.A.
20
N.A.
13.3
0
20
20
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
13.3
53.3
N.A.
26.6
N.A.
26.6
40
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
0
0
8
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
8
0
8
0
15
0
50
8
8
0
0
0
0
% D
% Glu:
22
8
15
0
8
0
22
15
0
58
8
8
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
58
% F
% Gly:
0
8
15
15
15
0
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
8
0
8
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
8
8
36
36
8
22
0
15
8
65
8
0
0
% K
% Leu:
15
58
8
0
0
15
8
8
0
0
0
0
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
29
0
8
0
22
0
15
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
0
15
0
8
15
15
15
0
8
0
0
% P
% Gln:
8
0
0
8
22
15
0
0
0
0
0
15
8
0
0
% Q
% Arg:
0
0
8
8
0
15
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
0
15
50
0
0
8
0
72
58
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% T
% Val:
22
0
0
43
0
0
0
0
0
8
43
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _