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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
22.73
Human Site:
T625
Identified Species:
38.46
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
T625
K
L
K
Q
L
T
K
T
G
K
A
S
F
I
K
Chimpanzee
Pan troglodytes
XP_515539
681
78871
T625
K
L
K
Q
L
T
K
T
G
K
A
S
F
I
K
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
T626
K
L
K
Q
L
T
K
T
G
K
A
S
F
I
K
Dog
Lupus familis
XP_849351
676
78277
T620
K
L
K
Q
L
T
K
T
G
K
A
S
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
T625
K
L
K
Q
L
T
K
T
G
K
V
S
L
L
K
Rat
Rattus norvegicus
NP_001099810
676
77809
T620
K
L
K
Q
L
T
K
T
G
K
V
S
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
G418
L
K
K
L
T
K
A
G
K
A
S
L
L
K
D
Chicken
Gallus gallus
XP_413769
665
76446
E609
K
L
K
K
L
T
K
E
G
K
A
S
L
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
G638
T
I
K
K
L
T
K
G
G
K
A
K
V
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
T605
A
D
A
K
L
L
K
T
I
T
K
N
R
N
V
Honey Bee
Apis mellifera
XP_394707
639
74546
K583
E
L
A
K
K
L
S
K
N
R
N
I
I
R
M
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
E590
A
V
K
L
A
K
K
E
R
K
A
G
K
E
K
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
A630
R
L
E
K
N
S
K
A
P
S
S
T
T
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
A539
L
K
R
K
R
S
K
A
N
L
P
N
V
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
73.3
N.A.
46.6
N.A.
20
6.6
33.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
13.3
86.6
N.A.
66.6
N.A.
33.3
26.6
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
0
8
0
8
15
0
8
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
8
0
0
0
0
15
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
58
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
8
8
22
8
% I
% Lys:
50
15
72
43
8
15
86
8
8
65
8
8
8
8
65
% K
% Leu:
15
65
0
15
65
15
0
0
0
8
0
8
36
36
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
15
0
8
15
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
8
0
0
0
8
8
0
0
8
8
0
% R
% Ser:
0
0
0
0
0
15
8
0
0
8
15
50
0
0
0
% S
% Thr:
8
0
0
0
8
58
0
50
0
8
0
8
8
8
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
15
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _