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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP56
All Species:
25.45
Human Site:
S251
Identified Species:
40
UniProt:
O00567
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00567
NP_006383.2
594
66050
S251
I
L
D
A
S
R
S
S
M
G
M
D
I
S
A
Chimpanzee
Pan troglodytes
XP_514472
779
85531
S436
I
L
D
A
S
R
S
S
M
G
M
D
I
S
A
Rhesus Macaque
Macaca mulatta
XP_001110561
587
65499
S244
I
L
D
A
S
R
S
S
M
G
M
D
I
S
A
Dog
Lupus familis
XP_851724
597
66425
S251
I
L
D
A
S
R
S
S
M
G
M
D
I
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6Z1
580
64446
S251
I
L
D
A
S
R
S
S
M
G
M
D
I
S
A
Rat
Rattus norvegicus
Q9QZ86
534
60052
S223
N
Y
A
S
A
T
L
S
E
F
L
S
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026559
535
59815
L223
F
I
G
N
R
K
E
L
S
E
E
S
L
E
G
Frog
Xenopus laevis
NP_001082151
532
59707
L223
F
I
G
N
R
K
E
L
S
E
E
K
L
E
E
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
E199
D
D
E
L
Q
R
L
E
E
A
C
D
M
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651040
496
54819
S187
D
K
D
V
N
T
F
S
M
R
I
R
E
W
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
L177
M
V
I
Q
S
I
A
L
L
D
Q
L
D
K
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318715
540
60255
S227
I
D
D
K
S
K
L
S
E
D
K
L
P
A
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
A216
L
M
G
N
R
V
N
A
A
K
L
D
F
S
E
Baker's Yeast
Sacchar. cerevisiae
Q12460
504
56846
V195
I
N
T
F
A
M
R
V
K
E
W
Y
G
W
H
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S244
V
K
A
A
A
D
I
S
M
G
T
E
V
S
E
Conservation
Percent
Protein Identity:
100
75.3
89.5
94.1
N.A.
89.9
38.2
N.A.
N.A.
71.5
70.1
20.5
N.A.
54.5
N.A.
48.9
N.A.
Protein Similarity:
100
75.8
92.2
96.3
N.A.
92.9
56.7
N.A.
N.A.
80.3
79.6
40.5
N.A.
66.5
N.A.
61.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
0
0
13.3
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
20
20
33.3
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
50.8
N.A.
N.A.
39
46.3
35
Protein Similarity:
66.1
N.A.
N.A.
57.4
61.7
52.7
P-Site Identity:
26.6
N.A.
N.A.
13.3
6.6
33.3
P-Site Similarity:
40
N.A.
N.A.
46.6
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
40
20
0
7
7
7
7
0
0
0
14
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
14
14
47
0
0
7
0
0
0
14
0
47
7
0
7
% D
% Glu:
0
0
7
0
0
0
14
7
20
20
14
7
14
20
20
% E
% Phe:
14
0
0
7
0
0
7
0
0
7
0
0
7
0
0
% F
% Gly:
0
0
20
0
0
0
0
0
0
40
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
47
14
7
0
0
7
7
0
0
0
7
0
34
0
0
% I
% Lys:
0
14
0
7
0
20
0
0
7
7
7
7
0
7
0
% K
% Leu:
7
34
0
7
0
0
20
20
7
0
14
14
14
0
14
% L
% Met:
7
7
0
0
0
7
0
0
47
0
34
0
7
0
0
% M
% Asn:
7
7
0
20
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
20
40
7
0
0
7
0
7
0
0
0
% R
% Ser:
0
0
0
7
47
0
34
60
14
0
0
14
0
47
0
% S
% Thr:
0
0
7
0
0
14
0
0
0
0
7
0
0
0
0
% T
% Val:
7
7
0
7
0
7
0
7
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _