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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP56
All Species:
18.18
Human Site:
S280
Identified Species:
28.57
UniProt:
O00567
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00567
NP_006383.2
594
66050
S280
S
L
S
E
Y
R
Q
S
L
H
T
Y
L
R
S
Chimpanzee
Pan troglodytes
XP_514472
779
85531
S465
S
L
S
E
Y
R
Q
S
L
H
T
Y
L
R
S
Rhesus Macaque
Macaca mulatta
XP_001110561
587
65499
S273
S
L
S
E
Y
R
Q
S
L
H
T
Y
L
R
S
Dog
Lupus familis
XP_851724
597
66425
S280
S
L
S
E
Y
R
Q
S
L
H
T
Y
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6Z1
580
64446
S280
S
L
S
E
Y
R
Q
S
L
H
T
Y
L
R
S
Rat
Rattus norvegicus
Q9QZ86
534
60052
C252
E
V
S
E
E
D
I
C
N
I
L
H
L
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026559
535
59815
M252
L
E
A
S
R
S
S
M
G
M
D
I
S
P
I
Frog
Xenopus laevis
NP_001082151
532
59707
M252
L
D
A
S
R
S
S
M
G
M
D
I
S
P
I
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
P228
S
R
M
S
F
I
A
P
N
L
S
I
I
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651040
496
54819
K216
Y
M
F
A
K
A
A
K
F
I
K
D
R
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
L206
H
Y
P
E
L
F
R
L
A
P
D
Q
Y
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318715
540
60255
G256
E
A
A
K
A
S
M
G
Q
D
L
S
P
I
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
V245
V
I
S
M
G
T
E
V
S
D
L
D
L
L
H
Baker's Yeast
Sacchar. cerevisiae
Q12460
504
56846
K224
A
K
L
V
L
F
I
K
D
K
A
S
L
N
D
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
Q273
D
Y
S
V
Y
R
K
Q
L
S
D
Y
L
E
N
Conservation
Percent
Protein Identity:
100
75.3
89.5
94.1
N.A.
89.9
38.2
N.A.
N.A.
71.5
70.1
20.5
N.A.
54.5
N.A.
48.9
N.A.
Protein Similarity:
100
75.8
92.2
96.3
N.A.
92.9
56.7
N.A.
N.A.
80.3
79.6
40.5
N.A.
66.5
N.A.
61.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
0
0
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
N.A.
6.6
6.6
26.6
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
50.8
N.A.
N.A.
39
46.3
35
Protein Similarity:
66.1
N.A.
N.A.
57.4
61.7
52.7
P-Site Identity:
0
N.A.
N.A.
13.3
6.6
40
P-Site Similarity:
13.3
N.A.
N.A.
26.6
13.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
20
7
7
7
14
0
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
7
7
0
0
0
7
0
0
7
14
27
14
0
0
14
% D
% Glu:
14
7
0
47
7
0
7
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
7
0
7
14
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
7
14
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
34
0
7
0
0
7
% H
% Ile:
0
7
0
0
0
7
14
0
0
14
0
20
7
7
14
% I
% Lys:
0
7
0
7
7
0
7
14
0
7
7
0
0
14
0
% K
% Leu:
14
34
7
0
14
0
0
7
40
7
20
0
60
7
0
% L
% Met:
0
7
7
7
0
0
7
14
0
14
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
0
0
0
0
7
14
% N
% Pro:
0
0
7
0
0
0
0
7
0
7
0
0
7
14
0
% P
% Gln:
0
0
0
0
0
0
34
7
7
0
0
7
0
0
0
% Q
% Arg:
0
7
0
0
14
40
7
0
0
0
0
0
7
34
0
% R
% Ser:
40
0
54
20
0
20
14
34
7
7
7
14
14
0
34
% S
% Thr:
0
0
0
0
0
7
0
0
0
0
34
0
0
0
7
% T
% Val:
7
7
0
14
0
0
0
7
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
14
0
0
40
0
0
0
0
0
0
40
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _