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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP56 All Species: 14.85
Human Site: S581 Identified Species: 23.33
UniProt: O00567 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00567 NP_006383.2 594 66050 S581 E A V G K S S S K K K K K F H
Chimpanzee Pan troglodytes XP_514472 779 85531 S766 E A A G K S T S K K K K K F H
Rhesus Macaque Macaca mulatta XP_001110561 587 65499 S574 E A A G K S S S K K K K K F H
Dog Lupus familis XP_851724 597 66425 S581 E E A A G N K S G S S K K K K
Cat Felis silvestris
Mouse Mus musculus Q9D6Z1 580 64446 T568 A N F T K S S T K K K K K S Q
Rat Rattus norvegicus Q9QZ86 534 60052 E521 S T A V P S P E K K K K K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026559 535 59815 L520 V M G E A T P L E K K K K K K
Frog Xenopus laevis NP_001082151 532 59707 P520 P E E A P Q K P K K K K K S K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 E496 K Y F S N M A E F L K V K R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651040 496 54819 K484 D G E P K K K K K K K N K N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21276 486 54493 K474 E V D E D A P K P K K K K K S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318715 540 60255 A526 D T E E L Q D A S G M K K K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 K521 T T E T P A K K K D K K E K K
Baker's Yeast Sacchar. cerevisiae Q12460 504 56846 K492 D K K E K K D K K E K K D K K
Red Bread Mold Neurospora crassa Q8X066 597 66063 S569 K P A K K S K S S K R K A E A
Conservation
Percent
Protein Identity: 100 75.3 89.5 94.1 N.A. 89.9 38.2 N.A. N.A. 71.5 70.1 20.5 N.A. 54.5 N.A. 48.9 N.A.
Protein Similarity: 100 75.8 92.2 96.3 N.A. 92.9 56.7 N.A. N.A. 80.3 79.6 40.5 N.A. 66.5 N.A. 61.9 N.A.
P-Site Identity: 100 86.6 93.3 26.6 N.A. 53.3 40 N.A. N.A. 26.6 33.3 13.3 N.A. 33.3 N.A. 33.3 N.A.
P-Site Similarity: 100 93.3 93.3 33.3 N.A. 60 40 N.A. N.A. 40 33.3 26.6 N.A. 40 N.A. 40 N.A.
Percent
Protein Identity: 50.8 N.A. N.A. 39 46.3 35
Protein Similarity: 66.1 N.A. N.A. 57.4 61.7 52.7
P-Site Identity: 13.3 N.A. N.A. 20 26.6 33.3
P-Site Similarity: 26.6 N.A. N.A. 33.3 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 34 14 7 14 7 7 0 0 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 7 0 7 0 14 0 0 7 0 0 7 0 0 % D
% Glu: 34 14 27 27 0 0 0 14 7 7 0 0 7 7 7 % E
% Phe: 0 0 14 0 0 0 0 0 7 0 0 0 0 20 0 % F
% Gly: 0 7 7 20 7 0 0 0 7 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 14 7 7 7 47 14 34 27 60 67 80 87 80 47 54 % K
% Leu: 0 0 0 0 7 0 0 7 0 7 0 0 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 0 0 7 7 0 0 0 0 0 7 0 7 0 % N
% Pro: 7 7 0 7 20 0 20 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % R
% Ser: 7 0 0 7 0 40 20 34 14 7 7 0 0 14 7 % S
% Thr: 7 20 0 14 0 7 7 7 0 0 0 0 0 0 0 % T
% Val: 7 7 7 7 0 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _