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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX1 All Species: 22.73
Human Site: Y120 Identified Species: 62.5
UniProt: O00570 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00570 NP_005977.2 391 39023 Y120 K E H P D Y K Y R P R R K T K
Chimpanzee Pan troglodytes XP_516895 690 75569 Y251 K E H P D Y K Y R P R R K T K
Rhesus Macaque Macaca mulatta NP_001136412 319 34405 I93 E T E K R P F I D E A K R L R
Dog Lupus familis XP_849239 403 39966 Y126 K E H P D Y K Y R P R R K T K
Cat Felis silvestris
Mouse Mus musculus P53783 391 39219 Y120 K E H P D Y K Y R P R R K T K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506984 290 31501 L70 F I D E A K R L R A L H M K E
Chicken Gallus gallus P48430 315 34493 I89 E A E K R P F I D E A K R L R
Frog Xenopus laevis Q2PG84 393 41040 Y103 K E H P D Y K Y R P R R K T K
Zebra Danio Brachydanio rerio Q2Z1R2 340 36419 Y106 K E H P D Y K Y R P R R K T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.3 54.2 94.7 N.A. 98.9 N.A. N.A. 50.6 51.4 75.5 69.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 39.1 63.6 95.2 N.A. 99.2 N.A. N.A. 59.3 60.3 80.1 74.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 N.A. N.A. 6.6 0 100 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 N.A. N.A. 20 26.6 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 12 0 0 0 0 12 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 67 0 0 0 23 0 0 0 0 0 0 % D
% Glu: 23 67 23 12 0 0 0 0 0 23 0 0 0 0 12 % E
% Phe: 12 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 67 0 0 0 0 0 0 0 0 12 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 23 0 0 0 0 0 0 0 % I
% Lys: 67 0 0 23 0 12 67 0 0 0 0 23 67 12 67 % K
% Leu: 0 0 0 0 0 0 0 12 0 0 12 0 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 67 0 23 0 0 0 67 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 23 0 12 0 78 0 67 67 23 0 23 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 12 0 0 0 0 0 0 0 0 0 0 0 67 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 67 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _