KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
26.06
Human Site:
S125
Identified Species:
40.95
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
S125
K
F
E
R
G
G
N
S
R
W
C
D
K
S
D
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S123
R
F
E
R
N
G
H
S
R
W
C
D
K
S
D
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
S375
K
F
E
R
G
G
N
S
R
W
C
D
K
S
D
Dog
Lupus familis
XP_861268
662
73195
S125
K
F
E
R
G
G
N
S
R
W
C
D
K
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
S125
K
F
E
R
G
G
N
S
R
W
C
D
K
S
D
Rat
Rattus norvegicus
NP_001102328
659
72976
S123
K
F
E
R
G
G
N
S
R
W
C
D
K
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
E119
R
W
S
D
K
S
D
E
D
D
W
S
K
P
L
Chicken
Gallus gallus
NP_001025971
651
72031
S123
N
S
R
W
C
D
K
S
D
E
D
D
W
S
K
Frog
Xenopus laevis
P24346
697
77284
R166
R
F
D
R
G
N
S
R
W
S
D
D
R
N
D
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
S153
G
F
G
G
G
G
N
S
R
W
V
E
E
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
R240
G
G
G
G
Y
N
S
R
W
K
E
G
G
G
S
Honey Bee
Apis mellifera
XP_391829
701
78642
R168
G
G
R
W
K
D
D
R
E
G
G
R
T
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
Q119
A
D
P
A
V
N
E
Q
E
N
T
V
I
N
F
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
L114
P
G
P
K
N
A
K
L
E
A
E
L
F
G
V
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
Q139
N
R
G
S
G
D
G
Q
W
R
D
G
K
H
I
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
93.3
N.A.
6.6
20
33.3
46.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
26.6
20
66.6
60
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
7
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
40
0
0
7
0
% C
% Asp:
0
7
7
7
0
20
14
0
14
7
20
54
0
0
47
% D
% Glu:
0
0
40
0
0
0
7
7
20
7
14
7
7
0
0
% E
% Phe:
0
54
0
0
0
0
0
0
0
0
0
0
7
0
7
% F
% Gly:
20
20
20
14
54
47
7
0
0
7
7
14
7
14
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% I
% Lys:
34
0
0
7
14
0
14
0
0
7
0
0
54
0
7
% K
% Leu:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
14
20
40
0
0
7
0
0
0
20
0
% N
% Pro:
7
0
14
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% Q
% Arg:
20
7
14
47
0
0
0
20
47
7
0
7
7
0
7
% R
% Ser:
0
7
7
7
0
7
14
54
0
7
0
7
0
40
14
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
7
7
0
0
7
% V
% Trp:
0
7
0
14
0
0
0
0
20
47
7
0
7
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _