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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3X All Species: 24.55
Human Site: S609 Identified Species: 38.57
UniProt: O00571 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00571 NP_001347.3 662 73243 S609 Y R Q S S G A S S S S F S S S
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S607 Y R Q S S G S S S S G F G A S
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 A858 D Y R Q S S G A S S S S F S S
Dog Lupus familis XP_861268 662 73195 S609 Y R Q S S G A S S S S F S S S
Cat Felis silvestris
Mouse Mus musculus Q62167 662 73083 S609 Y R Q S S G A S S S S F S S S
Rat Rattus norvegicus NP_001102328 659 72976 S606 Y R Q S S G A S S S S F S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 S595 Y R Q S S G A S S S S F S S S
Chicken Gallus gallus NP_001025971 651 72031 S598 A R D Y R T S S G A G S S S F
Frog Xenopus laevis P24346 697 77284 Q644 F G A K D Y R Q S S G A G S S
Zebra Danio Brachydanio rerio NP_571016 688 75828 N635 G A R D Y R Q N S S S G G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 G728 Y R Q S S G G G G G G R S G P
Honey Bee Apis mellifera XP_391829 701 78642 Q649 F G A R D Y R Q Q P S S G S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 A573 F S R G G G G A D Y Y G G G G
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 N565 G G F F N S R N N G S R D Y R
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 S621 D Y R K F G G S G G G G F G G
Conservation
Percent
Protein Identity: 100 91.3 70.1 99.8 N.A. 98.6 95.3 N.A. 95.9 91.2 82.2 76.3 N.A. 51.7 58 N.A. N.A.
Protein Similarity: 100 95.3 70.3 99.8 N.A. 99 97.1 N.A. 97.2 94.7 88 83.8 N.A. 63.4 70 N.A. N.A.
P-Site Identity: 100 73.3 40 100 N.A. 100 93.3 N.A. 100 26.6 26.6 20 N.A. 46.6 13.3 N.A. N.A.
P-Site Similarity: 100 86.6 53.3 100 N.A. 100 93.3 N.A. 100 40 33.3 33.3 N.A. 46.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 49.4 52
Protein Similarity: N.A. N.A. N.A. 64.6 65.2 64.8
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 14 0 0 0 34 14 0 7 0 7 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 7 7 14 0 0 0 7 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 20 0 7 7 7 0 0 0 0 0 0 40 14 0 7 % F
% Gly: 14 20 0 7 7 60 27 7 20 20 34 20 34 27 27 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 14 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % P
% Gln: 0 0 47 7 0 0 7 14 7 0 0 0 0 0 0 % Q
% Arg: 0 54 27 7 7 7 20 0 0 0 0 14 0 0 7 % R
% Ser: 0 7 0 47 54 14 14 54 60 60 60 20 47 60 47 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 14 0 7 7 14 0 0 0 7 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _