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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3X All Species: 53.94
Human Site: T323 Identified Species: 84.76
UniProt: O00571 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00571 NP_001347.3 662 73243 T323 G C H L L V A T P G R L V D M
Chimpanzee Pan troglodytes Q6GVM6 660 73172 T321 G C H L L V A T P G R L V D M
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 T573 G C H L L V A T P G R L V D M
Dog Lupus familis XP_861268 662 73195 T323 G C H L L V A T P G R L V D M
Cat Felis silvestris
Mouse Mus musculus Q62167 662 73083 T323 G C H L L V A T P G R L V D M
Rat Rattus norvegicus NP_001102328 659 72976 T321 G C H L L V A T P G R L V D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 T309 G C H L L V A T P G R L V D M
Chicken Gallus gallus NP_001025971 651 72031 T315 G C H L L V A T P G R L V D M
Frog Xenopus laevis P24346 697 77284 T364 G C H L L V A T P G R L V D M
Zebra Danio Brachydanio rerio NP_571016 688 75828 T355 G C H L L V A T P G R L L D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 T435 G C H L I V A T P G R L E D M
Honey Bee Apis mellifera XP_391829 701 78642 T361 G C H L L V A T P G R L V D M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 L302 S L Q M V R F L A L D E A D R
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 R297 L L V A T P G R L N D L L E R
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 T336 G C D L L V A T P G R L V D L
Conservation
Percent
Protein Identity: 100 91.3 70.1 99.8 N.A. 98.6 95.3 N.A. 95.9 91.2 82.2 76.3 N.A. 51.7 58 N.A. N.A.
Protein Similarity: 100 95.3 70.3 99.8 N.A. 99 97.1 N.A. 97.2 94.7 88 83.8 N.A. 63.4 70 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 86.6 100 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 49.4 52
Protein Similarity: N.A. N.A. N.A. 64.6 65.2 64.8
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 86.6
P-Site Similarity: N.A. N.A. N.A. 20 20 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 87 0 7 0 0 0 7 0 0 % A
% Cys: 0 87 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 14 0 0 94 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 7 7 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 87 0 0 0 0 0 7 0 0 87 0 0 0 0 0 % G
% His: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 14 0 87 80 0 0 7 7 7 0 94 14 0 7 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 80 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 87 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 7 0 7 0 0 87 0 0 0 14 % R
% Ser: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 87 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 7 87 0 0 0 0 0 0 74 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _