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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNASET2 All Species: 12.73
Human Site: S221 Identified Species: 20
UniProt: O00584 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00584 NP_003721.2 256 29481 S221 T E P G E Q P S P K Q E V W L
Chimpanzee Pan troglodytes XP_001136814 256 29469 S221 T E P G E Q P S P K Q E V W L
Rhesus Macaque Macaca mulatta XP_001101976 256 29554 S221 T E P G E Q L S P K Q K A W L
Dog Lupus familis XP_855271 220 24973 G180 P G E P G G P G G R D A L R G
Cat Felis silvestris
Mouse Mus musculus Q9CQ01 259 29590 S225 T E P G E Q L S S R Q E A W L
Rat Rattus norvegicus NP_001099680 256 29498 P222 C T E P E E Q P S S G Q E A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508676 219 25370 E184 N C T D P E V E S T K K T L M
Chicken Gallus gallus NP_001034580 266 31179 R224 E P K G E S S R M H T N L Q R
Frog Xenopus laevis NP_001086583 243 28313 I195 Q T L G Q I E I C F T K E F Q
Zebra Danio Brachydanio rerio NP_001025235 240 27415 I190 Q I L G Q I E I C V D R D F Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523966 325 37525 V274 K Q G D A V P V G V P G G T I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780287 309 34452 Y233 V P S K T N S Y D Y P T I F N
Poplar Tree Populus trichocarpa XP_002311302 227 25096 Q192 T D A S G N S Q L Y Q I Y L C
Maize Zea mays NP_001131005 229 25014 Q193 R D E A G N S Q L Y Q L Y F C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42813 230 25378 G192 E C N R D G S G N S Q L Y Q V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96 58.9 N.A. 68.3 67.5 N.A. 56.2 53.7 50.7 43.7 N.A. 25.8 N.A. N.A. 29.7
Protein Similarity: 100 99.2 97.6 64.4 N.A. 80.3 79.6 N.A. 71 66.9 67.1 60.5 N.A. 40.3 N.A. N.A. 45.3
P-Site Identity: 100 100 80 6.6 N.A. 73.3 6.6 N.A. 0 13.3 6.6 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 86.6 20 N.A. 80 20 N.A. 26.6 20 26.6 20 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: 30.8 30.4 N.A. 27.7 N.A. N.A.
Protein Similarity: 44.1 44.9 N.A. 43.3 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 0 0 0 0 0 0 7 14 7 0 % A
% Cys: 7 14 0 0 0 0 0 0 14 0 0 0 0 0 14 % C
% Asp: 0 14 0 14 7 0 0 0 7 0 14 0 7 0 0 % D
% Glu: 14 27 20 0 40 14 14 7 0 0 0 20 14 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 27 0 % F
% Gly: 0 7 7 47 20 14 0 14 14 0 7 7 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 14 0 14 0 0 0 7 7 0 7 % I
% Lys: 7 0 7 7 0 0 0 0 0 20 7 20 0 0 0 % K
% Leu: 0 0 14 0 0 0 14 0 14 0 0 14 14 14 27 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 7 0 7 0 0 20 0 0 7 0 0 7 0 0 7 % N
% Pro: 7 14 27 14 7 0 27 7 20 0 14 0 0 0 0 % P
% Gln: 14 7 0 0 14 27 7 14 0 0 47 7 0 14 14 % Q
% Arg: 7 0 0 7 0 0 0 7 0 14 0 7 0 7 14 % R
% Ser: 0 0 7 7 0 7 34 27 20 14 0 0 0 0 0 % S
% Thr: 34 14 7 0 7 0 0 0 0 7 14 7 7 7 0 % T
% Val: 7 0 0 0 0 7 7 7 0 14 0 0 14 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 20 0 0 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _