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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFNG
All Species:
21.52
Human Site:
S224
Identified Species:
47.33
UniProt:
O00587
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00587
NP_002396.2
321
36202
S224
G
S
R
F
M
D
T
S
A
L
I
R
L
P
D
Chimpanzee
Pan troglodytes
Q5IS64
321
36335
S224
G
S
R
F
M
D
T
S
A
L
I
R
L
P
D
Rhesus Macaque
Macaca mulatta
XP_001087991
311
35084
S214
G
S
R
F
M
D
T
S
A
L
I
R
L
P
D
Dog
Lupus familis
XP_852869
315
35552
S222
G
S
R
F
V
E
T
S
A
L
I
R
L
P
D
Cat
Felis silvestris
Mouse
Mus musculus
O09008
321
36181
S224
G
S
H
F
V
D
T
S
A
L
I
R
L
P
D
Rat
Rattus norvegicus
Q924T4
378
41940
A281
G
G
H
F
M
S
T
A
E
R
I
R
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521629
337
37746
S240
G
P
R
F
Q
N
T
S
T
L
I
R
L
P
D
Chicken
Gallus gallus
O12971
363
40639
A266
G
G
H
F
M
S
T
A
E
K
I
R
L
P
D
Frog
Xenopus laevis
P79948
375
42115
A278
G
G
H
F
M
N
T
A
E
K
I
R
L
P
D
Zebra Danio
Brachydanio rerio
Q8JHF2
374
41863
A277
G
G
H
F
M
N
T
A
E
K
I
R
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24342
412
46973
G319
G
G
K
F
I
S
I
G
D
K
I
R
F
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
77.8
86.9
N.A.
82.8
52.9
N.A.
69.7
52.6
49.5
50.7
N.A.
35.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99
79.4
91.5
N.A.
89
63.7
N.A.
81
65.2
62.9
65.2
N.A.
48.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
60
N.A.
73.3
60
60
60
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
66.6
N.A.
80
66.6
73.3
73.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
37
46
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
37
0
0
10
0
0
0
0
0
100
% D
% Glu:
0
0
0
0
0
10
0
0
37
0
0
0
0
0
0
% E
% Phe:
0
0
0
100
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
100
46
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
37
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
55
0
0
91
0
0
% L
% Met:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
46
0
0
0
0
0
0
10
0
100
0
0
0
% R
% Ser:
0
46
0
0
0
28
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
91
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _