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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFNG All Species: 32.73
Human Site: T77 Identified Species: 72
UniProt: O00587 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00587 NP_002396.2 321 36202 T77 R L E L L L D T W V S R T R E
Chimpanzee Pan troglodytes Q5IS64 321 36335 T77 R L E L L L D T W V S R T R E
Rhesus Macaque Macaca mulatta XP_001087991 311 35084 L67 G L T W P T A L S C L V P I T
Dog Lupus familis XP_852869 315 35552 T75 R L E L L L D T W V S R T R E
Cat Felis silvestris
Mouse Mus musculus O09008 321 36181 T77 R L D L L L D T W V S R I R Q
Rat Rattus norvegicus Q924T4 378 41940 E134 A R L D L L F E T W I S R H K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521629 337 37746 T93 R L E L L L D T W I S R T R K
Chicken Gallus gallus O12971 363 40639 T120 R L E L L L D T W I S R N R D
Frog Xenopus laevis P79948 375 42115 T132 R M D L L M D T W I S R N K E
Zebra Danio Brachydanio rerio Q8JHF2 374 41863 T130 R L D L L L D T W I S R N M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24342 412 46973 T171 R L A L I I K T W F Q L A R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 77.8 86.9 N.A. 82.8 52.9 N.A. 69.7 52.6 49.5 50.7 N.A. 35.9 N.A. N.A. N.A.
Protein Similarity: 100 99 79.4 91.5 N.A. 89 63.7 N.A. 81 65.2 62.9 65.2 N.A. 48.5 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 80 13.3 N.A. 86.6 80 60 66.6 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 93.3 20 N.A. 100 93.3 93.3 80 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 10 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 28 10 0 0 73 0 0 0 0 0 0 0 19 % D
% Glu: 0 0 46 0 0 0 0 10 0 0 0 0 0 0 37 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 37 10 0 10 10 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 19 % K
% Leu: 0 82 10 82 82 73 0 10 0 0 10 10 0 0 0 % L
% Met: 0 10 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % Q
% Arg: 82 10 0 0 0 0 0 0 0 0 0 73 10 64 10 % R
% Ser: 0 0 0 0 0 0 0 0 10 0 73 10 0 0 0 % S
% Thr: 0 0 10 0 0 10 0 82 10 0 0 0 37 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 37 0 10 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 82 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _