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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FCN1
All Species:
26.36
Human Site:
S181
Identified Species:
82.86
UniProt:
O00602
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00602
NP_001994.2
326
35078
S181
A
Y
K
Q
G
F
G
S
Q
L
G
E
F
W
L
Chimpanzee
Pan troglodytes
XP_001170643
326
34959
S181
A
Y
K
Q
G
F
G
S
Q
L
G
E
F
W
L
Rhesus Macaque
Macaca mulatta
XP_001098002
326
35135
S181
A
Y
K
Q
G
F
G
S
R
L
G
E
F
W
L
Dog
Lupus familis
XP_850307
322
34513
S177
S
Y
K
Q
G
F
G
S
Q
L
G
E
F
W
L
Cat
Felis silvestris
Mouse
Mus musculus
O70497
314
33966
S169
S
Y
K
R
G
F
G
S
Q
L
G
E
F
W
L
Rat
Rattus norvegicus
P57756
319
34665
S174
S
Y
K
Q
G
F
G
S
Q
L
G
E
F
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509559
365
39171
S220
T
Y
K
K
G
F
G
S
Q
L
A
G
F
W
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6AX44
457
50990
K304
Q
Y
R
D
G
F
G
K
L
T
G
E
H
W
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
91.7
72.3
N.A.
71.7
75.4
N.A.
47.6
N.A.
33.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
95.4
83.1
N.A.
82.5
84
N.A.
61
N.A.
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
88
0
0
% F
% Gly:
0
0
0
0
100
0
100
0
0
0
88
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
88
13
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
13
88
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
63
0
0
0
0
75
0
0
0
0
0
0
% Q
% Arg:
0
0
13
13
0
0
0
0
13
0
0
0
0
0
0
% R
% Ser:
38
0
0
0
0
0
0
88
0
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% W
% Tyr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _