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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX12 All Species: 17.88
Human Site: S12 Identified Species: 26.22
UniProt: O00623 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00623 NP_000277.1 359 40797 S12 G A H F T A A S V A D D Q P S
Chimpanzee Pan troglodytes XP_001174172 359 40821 S12 G A H F T A A S V A D D Q P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548259 359 40831 A12 G A H I T T A A V V D D Q P S
Cat Felis silvestris
Mouse Mus musculus Q8VC48 359 40614 S12 G A H I T T A S V A D D Q P S
Rat Rattus norvegicus O88177 359 40663 S12 G A H I T T A S V A D D Q P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511496 312 33803
Chicken Gallus gallus XP_415773 356 39947 A12 G A H L T A E A A G D D R P S
Frog Xenopus laevis NP_001086511 353 40718 T11 R G A H I T T T S P L D D R P
Zebra Danio Brachydanio rerio NP_956499 303 34092
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPT5 297 34525
Honey Bee Apis mellifera XP_624974 285 32991
Nematode Worm Caenorhab. elegans Q19189 359 41271 S13 R A S Q L A S S I S P K T E E
Sea Urchin Strong. purpuratus XP_788130 354 40571 A11 F G A H L T S A T T D N R P S
Poplar Tree Populus trichocarpa XP_002325774 388 43941 T13 G G Q G T R P T F F E M A A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M841 393 44382 T13 G G E G T R P T F F E M A A A
Baker's Yeast Sacchar. cerevisiae Q04370 399 45974 G26 T S G R N G V G L E P L Y P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 92.1 N.A. 89.4 88.5 N.A. 46.7 76 64 51.5 N.A. 29.8 31.7 35.9 45.6
Protein Similarity: 100 99.7 N.A. 96 N.A. 93.3 92.7 N.A. 57.3 85.7 79.6 65.4 N.A. 47 49 56.2 68.5
P-Site Identity: 100 100 N.A. 73.3 N.A. 86.6 86.6 N.A. 0 60 6.6 0 N.A. 0 0 20 20
P-Site Similarity: 100 100 N.A. 80 N.A. 86.6 86.6 N.A. 0 73.3 13.3 0 N.A. 0 0 40 46.6
Percent
Protein Identity: 31.9 N.A. N.A. 31.3 22.3 N.A.
Protein Similarity: 48.7 N.A. N.A. 48.3 40.3 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 44 13 0 0 25 32 19 7 25 0 0 13 13 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 44 44 7 0 0 % D
% Glu: 0 0 7 0 0 0 7 0 0 7 13 0 0 7 7 % E
% Phe: 7 0 0 13 0 0 0 0 13 13 0 0 0 0 0 % F
% Gly: 50 25 7 13 0 7 0 7 0 7 0 0 0 0 0 % G
% His: 0 0 38 13 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 7 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 0 7 13 0 0 0 7 0 7 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 13 0 0 7 13 0 0 50 7 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 0 0 32 0 0 % Q
% Arg: 13 0 0 7 0 13 0 0 0 0 0 0 13 7 0 % R
% Ser: 0 7 7 0 0 0 13 32 7 7 0 0 0 0 44 % S
% Thr: 7 0 0 0 50 32 7 19 7 7 0 0 7 0 7 % T
% Val: 0 0 0 0 0 0 7 0 32 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _