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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
23.64
Human Site:
S135
Identified Species:
34.67
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
S135
V
K
L
E
K
L
V
S
S
L
R
E
E
D
E
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
S135
V
K
L
E
K
L
V
S
S
L
R
E
E
D
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
S135
V
K
L
E
K
L
I
S
S
L
R
E
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
S135
V
K
L
E
K
L
A
S
S
L
R
E
E
D
E
Rat
Rattus norvegicus
O88177
359
40663
S135
V
K
L
E
K
L
A
S
T
L
R
E
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
R92
E
N
F
Y
G
L
K
R
V
A
T
G
A
G
P
Chicken
Gallus gallus
XP_415773
356
39947
S134
G
K
L
E
K
L
V
S
S
L
R
E
E
D
E
Frog
Xenopus laevis
NP_001086511
353
40718
R133
E
K
L
V
N
S
L
R
E
E
E
D
Y
S
I
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
F82
L
S
R
T
S
A
S
F
S
E
N
F
Y
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
S77
L
Y
L
R
K
R
A
S
S
F
G
E
S
F
Y
Honey Bee
Apis mellifera
XP_624974
285
32991
E65
D
E
S
A
S
F
S
E
T
F
Y
S
L
K
R
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
K136
N
Q
L
Y
D
R
L
K
E
V
Y
E
C
R
S
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
F133
K
L
K
L
D
A
K
F
Q
K
W
T
D
E
S
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
N136
S
K
L
Y
S
I
Y
N
K
E
R
E
A
R
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
N136
S
K
L
H
A
I
Y
N
K
E
R
E
A
R
L
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
P151
F
L
E
K
I
I
L
P
Y
I
T
A
K
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
6.6
93.3
13.3
6.6
N.A.
33.3
0
13.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
93.3
26.6
13.3
N.A.
40
13.3
33.3
13.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
13
19
0
0
7
0
7
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
13
0
0
0
0
0
0
7
7
38
7
% D
% Glu:
13
7
7
38
0
0
0
7
13
25
7
63
38
7
38
% E
% Phe:
7
0
7
0
0
7
0
13
0
13
0
7
0
7
0
% F
% Gly:
7
0
0
0
7
0
0
0
0
0
7
7
0
13
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
19
7
0
0
7
0
0
0
0
7
% I
% Lys:
7
57
7
7
44
0
13
7
13
7
0
0
7
7
0
% K
% Leu:
13
13
69
7
0
44
19
0
0
38
0
0
7
7
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
7
0
0
13
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
0
13
0
13
0
0
50
0
0
19
7
% R
% Ser:
13
7
7
0
19
7
13
44
44
0
0
7
7
7
13
% S
% Thr:
0
0
0
7
0
0
0
0
13
0
13
7
0
0
0
% T
% Val:
32
0
0
7
0
0
19
0
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
19
0
0
13
0
7
0
13
0
13
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _