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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX12 All Species: 26.36
Human Site: S136 Identified Species: 38.67
UniProt: O00623 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00623 NP_000277.1 359 40797 S136 K L E K L V S S L R E E D E Y
Chimpanzee Pan troglodytes XP_001174172 359 40821 S136 K L E K L V S S L R E E D E Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548259 359 40831 S136 K L E K L I S S L R E E D E Y
Cat Felis silvestris
Mouse Mus musculus Q8VC48 359 40614 S136 K L E K L A S S L R E E D E Y
Rat Rattus norvegicus O88177 359 40663 T136 K L E K L A S T L R E E D E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511496 312 33803 V93 N F Y G L K R V A T G A G P G
Chicken Gallus gallus XP_415773 356 39947 S135 K L E K L V S S L R E E D E Y
Frog Xenopus laevis NP_001086511 353 40718 E134 K L V N S L R E E E D Y S I Q
Zebra Danio Brachydanio rerio NP_956499 303 34092 S83 S R T S A S F S E N F Y G L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPT5 297 34525 S78 Y L R K R A S S F G E S F Y G
Honey Bee Apis mellifera XP_624974 285 32991 T66 E S A S F S E T F Y S L K R I
Nematode Worm Caenorhab. elegans Q19189 359 41271 E137 Q L Y D R L K E V Y E C R S W
Sea Urchin Strong. purpuratus XP_788130 354 40571 Q134 L K L D A K F Q K W T D E S L
Poplar Tree Populus trichocarpa XP_002325774 388 43941 K137 K L Y S I Y N K E R E A R L Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M841 393 44382 K137 K L H A I Y N K E R E A R L R
Baker's Yeast Sacchar. cerevisiae Q04370 399 45974 Y152 L E K I I L P Y I T A K L D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 92.1 N.A. 89.4 88.5 N.A. 46.7 76 64 51.5 N.A. 29.8 31.7 35.9 45.6
Protein Similarity: 100 99.7 N.A. 96 N.A. 93.3 92.7 N.A. 57.3 85.7 79.6 65.4 N.A. 47 49 56.2 68.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 86.6 N.A. 6.6 100 13.3 6.6 N.A. 33.3 0 13.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 6.6 100 26.6 6.6 N.A. 33.3 13.3 40 13.3
Percent
Protein Identity: 31.9 N.A. N.A. 31.3 22.3 N.A.
Protein Similarity: 48.7 N.A. N.A. 48.3 40.3 N.A.
P-Site Identity: 26.6 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 40 N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 13 19 0 0 7 0 7 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 0 7 7 38 7 0 % D
% Glu: 7 7 38 0 0 0 7 13 25 7 63 38 7 38 7 % E
% Phe: 0 7 0 0 7 0 13 0 13 0 7 0 7 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 7 7 0 13 0 13 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 19 7 0 0 7 0 0 0 0 7 7 % I
% Lys: 57 7 7 44 0 13 7 13 7 0 0 7 7 0 7 % K
% Leu: 13 69 7 0 44 19 0 0 38 0 0 7 7 19 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 0 0 13 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % P
% Gln: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 13 % Q
% Arg: 0 7 7 0 13 0 13 0 0 50 0 0 19 7 7 % R
% Ser: 7 7 0 19 7 13 44 44 0 0 7 7 7 13 0 % S
% Thr: 0 0 7 0 0 0 0 13 0 13 7 0 0 0 0 % T
% Val: 0 0 7 0 0 19 0 7 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % W
% Tyr: 7 0 19 0 0 13 0 7 0 13 0 13 0 7 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _