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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX12 All Species: 23.33
Human Site: S144 Identified Species: 34.22
UniProt: O00623 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00623 NP_000277.1 359 40797 S144 L R E E D E Y S I H P P S S R
Chimpanzee Pan troglodytes XP_001174172 359 40821 S144 L R E E D E Y S I H P P S S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548259 359 40831 S144 L R E E D E Y S I H P P S S R
Cat Felis silvestris
Mouse Mus musculus Q8VC48 359 40614 S144 L R E E D E Y S I H P P S S R
Rat Rattus norvegicus O88177 359 40663 S144 L R E E D E Y S I H P P S S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511496 312 33803 R101 A T G A G P G R P A G G P G L
Chicken Gallus gallus XP_415773 356 39947 S143 L R E E D E Y S I H P P S S S
Frog Xenopus laevis NP_001086511 353 40718 N142 E E D Y S I Q N P T S F H K R
Zebra Danio Brachydanio rerio NP_956499 303 34092 R91 E N F Y G L K R V G S H S A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPT5 297 34525 L86 F G E S F Y G L Q R T V T T T
Honey Bee Apis mellifera XP_624974 285 32991 I74 F Y S L K R I I I V N S K V K
Nematode Worm Caenorhab. elegans Q19189 359 41271 S145 V Y E C R S W S S I N G M K A
Sea Urchin Strong. purpuratus XP_788130 354 40571 D142 K W T D E S L D L N D R G R Q
Poplar Tree Populus trichocarpa XP_002325774 388 43941 A145 E R E A R L Q A S L W G N G D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M841 393 44382 E145 E R E A R L R E S L W G A E D
Baker's Yeast Sacchar. cerevisiae Q04370 399 45974 I160 I T A K L D E I L E K I S M N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 92.1 N.A. 89.4 88.5 N.A. 46.7 76 64 51.5 N.A. 29.8 31.7 35.9 45.6
Protein Similarity: 100 99.7 N.A. 96 N.A. 93.3 92.7 N.A. 57.3 85.7 79.6 65.4 N.A. 47 49 56.2 68.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 0 93.3 6.6 13.3 N.A. 6.6 6.6 13.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 0 93.3 20 26.6 N.A. 20 13.3 26.6 33.3
Percent
Protein Identity: 31.9 N.A. N.A. 31.3 22.3 N.A.
Protein Similarity: 48.7 N.A. N.A. 48.3 40.3 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 19 0 0 0 7 0 7 0 0 7 7 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 38 7 0 7 0 0 7 0 0 0 13 % D
% Glu: 25 7 63 38 7 38 7 7 0 7 0 0 0 7 0 % E
% Phe: 13 0 7 0 7 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 7 7 0 13 0 13 0 0 7 7 25 7 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 38 0 7 7 0 7 % H
% Ile: 7 0 0 0 0 7 7 13 44 7 0 7 0 0 0 % I
% Lys: 7 0 0 7 7 0 7 0 0 0 7 0 7 13 7 % K
% Leu: 38 0 0 7 7 19 7 7 13 13 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 7 0 0 0 0 0 7 0 7 13 0 7 0 7 % N
% Pro: 0 0 0 0 0 7 0 0 13 0 38 38 7 0 0 % P
% Gln: 0 0 0 0 0 0 13 0 7 0 0 0 0 0 7 % Q
% Arg: 0 50 0 0 19 7 7 13 0 7 0 7 0 7 38 % R
% Ser: 0 0 7 7 7 13 0 44 19 0 13 7 50 38 7 % S
% Thr: 0 13 7 0 0 0 0 0 0 7 7 0 7 7 7 % T
% Val: 7 0 0 0 0 0 0 0 7 7 0 7 0 7 0 % V
% Trp: 0 7 0 0 0 0 7 0 0 0 13 0 0 0 0 % W
% Tyr: 0 13 0 13 0 7 38 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _