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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
19.39
Human Site:
Y290
Identified Species:
28.44
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Rat
Rattus norvegicus
O88177
359
40663
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
V244
W
L
V
F
L
P
L
V
P
F
P
E
R
R
L
Chicken
Gallus gallus
XP_415773
356
39947
H287
P
P
P
V
H
L
D
H
G
V
D
S
A
L
L
Frog
Xenopus laevis
NP_001086511
353
40718
E285
P
P
I
H
F
D
L
E
T
Y
S
P
L
L
P
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
G235
R
V
V
S
A
A
V
G
G
V
A
V
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
Q229
P
E
A
M
P
R
K
Q
L
P
K
E
V
Q
Q
Honey Bee
Apis mellifera
XP_624974
285
32991
S217
L
L
S
L
P
I
P
S
P
P
K
I
P
E
I
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
P289
D
G
A
I
P
S
P
P
H
K
M
I
I
S
E
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
P285
E
P
P
K
E
R
E
P
E
Y
C
Q
I
L
L
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
V320
P
P
P
P
A
P
K
V
A
K
E
G
I
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
M325
P
P
P
P
A
P
K
M
A
K
E
G
I
P
L
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
H320
P
R
P
P
F
S
S
H
S
D
K
T
E
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
73.3
20
6.6
N.A.
6.6
6.6
0
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
80
20
6.6
N.A.
13.3
26.6
13.3
33.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
19
7
0
0
13
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
38
0
0
7
38
0
0
7
0
% D
% Glu:
7
7
0
0
7
0
7
7
7
0
13
13
7
7
7
% E
% Phe:
0
0
0
7
13
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
7
13
0
0
13
0
0
0
% G
% His:
0
0
0
7
38
0
0
13
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
7
0
0
0
0
0
13
25
0
7
% I
% Lys:
0
0
0
7
0
0
19
0
0
19
19
0
0
0
7
% K
% Leu:
7
13
0
7
7
38
13
0
7
0
0
0
7
57
63
% L
% Met:
0
0
0
7
0
0
0
7
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
32
0
0
0
0
0
0
% N
% Pro:
69
63
63
19
19
19
13
13
13
13
7
7
38
13
7
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
7
% Q
% Arg:
7
7
0
0
0
13
0
0
0
0
0
0
7
7
0
% R
% Ser:
0
0
7
7
0
13
7
7
7
32
7
38
7
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% T
% Val:
0
7
13
38
0
0
7
13
0
13
0
7
7
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
32
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _