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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIR All Species: 17.88
Human Site: S17 Identified Species: 35.76
UniProt: O00625 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00625 NP_001018119.1 290 32113 S17 S V L S R E Q S E G V G A R V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116938 271 30152 M19 A D I G E E L M R F L F Y Q K
Dog Lupus familis XP_537963 290 32131 A17 S V L S R E Q A E G V G A R V
Cat Felis silvestris
Mouse Mus musculus Q9D711 290 32048 S17 S V L S R E Q S E G V G A R V
Rat Rattus norvegicus Q5M827 291 32160 S17 S V L S R E Q S E G V G A R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517091 291 32246 S17 T V L S Q E Q S E G V G A R V
Chicken Gallus gallus
Frog Xenopus laevis NP_001079619 290 32211 L35 G R V E L K N L D P F L M L D
Zebra Danio Brachydanio rerio Q7SXP8 422 46989 F86 P I R Y L Q E F A A L G T G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789037 294 32330 S20 S V L S V E Q S E G V G A R V
Poplar Tree Populus trichocarpa XP_002302888 294 32622 H26 K V L A K L Q H E G E G A V V
Maize Zea mays NP_001150652 331 36420 P64 K V L A Q S Q P E G Q G A T V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZW82 321 35520 K49 K V F A K L Q K E G D G A V V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 69.6 96.2 N.A. 95.8 95.1 N.A. 89.3 N.A. 76.2 20.3 N.A. N.A. N.A. N.A. 61.2
Protein Similarity: 100 N.A. 77.5 98.6 N.A. 97.9 96.9 N.A. 96.9 N.A. 86.5 35.5 N.A. N.A. N.A. N.A. 75.1
P-Site Identity: 100 N.A. 6.6 93.3 N.A. 100 100 N.A. 86.6 N.A. 0 6.6 N.A. N.A. N.A. N.A. 93.3
P-Site Similarity: 100 N.A. 33.3 100 N.A. 100 100 N.A. 100 N.A. 20 33.3 N.A. N.A. N.A. N.A. 93.3
Percent
Protein Identity: 55.1 48 N.A. 49.8 N.A. N.A.
Protein Similarity: 70 62.8 N.A. 62.6 N.A. N.A.
P-Site Identity: 53.3 53.3 N.A. 46.6 N.A. N.A.
P-Site Similarity: 66.6 66.6 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 25 0 0 0 9 9 9 0 0 75 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 9 0 9 0 0 0 9 % D
% Glu: 0 0 0 9 9 59 9 0 75 0 9 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 9 9 9 0 0 0 % F
% Gly: 9 0 0 9 0 0 0 0 0 75 0 84 0 9 9 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 0 0 0 17 9 0 9 0 0 0 0 0 0 9 % K
% Leu: 0 0 67 0 17 17 9 9 0 0 17 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 17 9 75 0 0 0 9 0 0 9 0 % Q
% Arg: 0 9 9 0 34 0 0 0 9 0 0 0 0 50 0 % R
% Ser: 42 0 0 50 0 9 0 42 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % T
% Val: 0 75 9 0 9 0 0 0 0 0 50 0 0 17 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _