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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIR All Species: 31.82
Human Site: S27 Identified Species: 63.64
UniProt: O00625 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00625 NP_001018119.1 290 32113 S27 V G A R V R R S I G R P E L K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116938 271 30152 Y29 L F Y Q K V S Y L L E G G S M
Dog Lupus familis XP_537963 290 32131 S27 V G A R V R R S I G R P E L K
Cat Felis silvestris
Mouse Mus musculus Q9D711 290 32048 S27 V G A R V R R S I G R P E L K
Rat Rattus norvegicus Q5M827 291 32160 S27 V G A R V R R S I G G P E L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517091 291 32246 S27 V G A R V R R S I G R P E L R
Chicken Gallus gallus
Frog Xenopus laevis NP_001079619 290 32211 K45 F L M L D E F K G G K P A G F
Zebra Danio Brachydanio rerio Q7SXP8 422 46989 Y96 L G T G G G I Y H F R D Q I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789037 294 32330 S30 V G A R V R R S I G R Q E L R
Poplar Tree Populus trichocarpa XP_002302888 294 32622 S36 E G A V V R R S I G R S E L K
Maize Zea mays NP_001150652 331 36420 S74 Q G A T V R R S I G R H E L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZW82 321 35520 G59 D G A V V R R G I S R S E Q K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 69.6 96.2 N.A. 95.8 95.1 N.A. 89.3 N.A. 76.2 20.3 N.A. N.A. N.A. N.A. 61.2
Protein Similarity: 100 N.A. 77.5 98.6 N.A. 97.9 96.9 N.A. 96.9 N.A. 86.5 35.5 N.A. N.A. N.A. N.A. 75.1
P-Site Identity: 100 N.A. 0 100 N.A. 100 93.3 N.A. 93.3 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. 86.6
P-Site Similarity: 100 N.A. 20 100 N.A. 100 93.3 N.A. 100 N.A. 20 33.3 N.A. N.A. N.A. N.A. 93.3
Percent
Protein Identity: 55.1 48 N.A. 49.8 N.A. N.A.
Protein Similarity: 70 62.8 N.A. 62.6 N.A. N.A.
P-Site Identity: 80 73.3 N.A. 60 N.A. N.A.
P-Site Similarity: 80 80 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 75 0 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 9 0 0 0 0 9 0 0 0 0 9 0 75 0 0 % E
% Phe: 9 9 0 0 0 0 9 0 0 9 0 0 0 0 9 % F
% Gly: 0 84 0 9 9 9 0 9 9 75 9 9 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 75 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 9 0 0 9 0 0 9 0 0 0 50 % K
% Leu: 17 9 0 9 0 0 0 0 9 9 0 0 0 67 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 9 9 9 0 % Q
% Arg: 0 0 0 50 0 75 75 0 0 0 75 0 0 0 25 % R
% Ser: 0 0 0 0 0 0 9 67 0 9 0 17 0 9 0 % S
% Thr: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 50 0 0 17 75 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 17 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _