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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIR
All Species:
32.42
Human Site:
Y131
Identified Species:
64.85
UniProt:
O00625
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00625
NP_001018119.1
290
32113
Y131
E
K
M
V
E
P
Q
Y
Q
E
L
K
S
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116938
271
30152
V112
P
S
R
D
G
V
T
V
A
V
I
S
G
E
A
Dog
Lupus familis
XP_537963
290
32131
Y131
E
K
M
V
E
P
Q
Y
Q
E
L
K
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D711
290
32048
Y131
E
K
M
V
A
P
Q
Y
Q
E
L
K
S
E
E
Rat
Rattus norvegicus
Q5M827
291
32160
Y131
E
K
M
V
E
P
Q
Y
Q
E
L
K
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517091
291
32246
Y131
E
K
M
V
E
P
H
Y
Q
E
L
K
N
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079619
290
32211
Y130
E
K
M
I
P
P
Q
Y
Q
E
L
K
C
S
D
Zebra Danio
Brachydanio rerio
Q7SXP8
422
46989
L212
Q
E
K
I
Q
E
E
L
T
H
G
R
Q
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789037
294
32330
Y133
F
K
M
V
E
P
E
Y
Q
E
L
Q
A
K
N
Poplar Tree
Populus trichocarpa
XP_002302888
294
32622
Y139
D
K
M
I
E
P
G
Y
Q
E
L
L
S
D
D
Maize
Zea mays
NP_001150652
331
36420
Q178
K
M
I
E
P
R
Y
Q
E
L
E
R
K
D
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZW82
321
35520
Y161
E
K
M
I
E
P
N
Y
Q
E
L
S
H
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.6
96.2
N.A.
95.8
95.1
N.A.
89.3
N.A.
76.2
20.3
N.A.
N.A.
N.A.
N.A.
61.2
Protein Similarity:
100
N.A.
77.5
98.6
N.A.
97.9
96.9
N.A.
96.9
N.A.
86.5
35.5
N.A.
N.A.
N.A.
N.A.
75.1
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
100
N.A.
80
N.A.
66.6
0
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
N.A.
13.3
100
N.A.
93.3
100
N.A.
93.3
N.A.
80
40
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
55.1
48
N.A.
49.8
N.A.
N.A.
Protein Similarity:
70
62.8
N.A.
62.6
N.A.
N.A.
P-Site Identity:
60
0
N.A.
60
N.A.
N.A.
P-Site Similarity:
86.6
33.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
0
0
0
17
25
% D
% Glu:
59
9
0
9
59
9
17
0
9
75
9
0
0
34
42
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
9
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% H
% Ile:
0
0
9
34
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
9
75
9
0
0
0
0
0
0
0
0
50
9
25
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
9
75
9
0
0
0
% L
% Met:
0
9
75
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
17
75
0
0
0
0
0
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
42
9
75
0
0
9
9
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
0
0
17
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
0
0
0
0
17
42
17
0
% S
% Thr:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
50
0
9
0
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _