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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX7 All Species: 27.27
Human Site: S222 Identified Species: 46.15
UniProt: O00628 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00628 NP_000279.1 323 35892 S222 V T G A V D C S L R G W D L R
Chimpanzee Pan troglodytes XP_518763 323 35901 S222 V T G A V D C S L R G W D L R
Rhesus Macaque Macaca mulatta XP_001097630 323 35946 S222 V T G A V D C S L R G W D L R
Dog Lupus familis XP_541117 323 36007 S222 V T G A V D C S L R G W D L R
Cat Felis silvestris
Mouse Mus musculus P97865 318 35483 S217 V T G A V D C S L R G W D L R
Rat Rattus norvegicus Q5M7T1 339 37599 W241 C S G S D P S W K C V C T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516140 223 24840 A128 P H I P G C F A S A S G D Q T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T394 410 46494 T257 A S S S N D Q T V R V W V V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 L221 V S S S Y D G L C R I W D T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90916 417 47148 K246 G S V G D D K K L L I W D V R
Sea Urchin Strong. purpuratus XP_001182039 234 26504 R139 K I R G W D L R N P T K I L F
Poplar Tree Populus trichocarpa XP_002305744 318 35680 S217 A T A S V D K S I K V W D V R
Maize Zea mays NP_001130205 319 35161 S218 A T A S V D K S I R V W D V R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39108 375 42304 A244 A T G G V D N A I R I W D I R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.8 92.5 N.A. 91 20 N.A. 61.6 N.A. N.A. 21.9 N.A. 26.3 N.A. 25.4 39.6
Protein Similarity: 100 99 98.4 95.6 N.A. 94.1 38 N.A. 66.5 N.A. N.A. 39 N.A. 43.2 N.A. 39 53.8
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 N.A. N.A. 20 N.A. 33.3 N.A. 33.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 13.3 N.A. N.A. 53.3 N.A. 46.6 N.A. 46.6 13.3
Percent
Protein Identity: 42.1 42.7 N.A. N.A. 29.3 N.A.
Protein Similarity: 61.6 60.9 N.A. N.A. 48 N.A.
P-Site Identity: 46.6 53.3 N.A. N.A. 53.3 N.A.
P-Site Similarity: 73.3 73.3 N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 15 36 0 0 0 15 0 8 0 0 0 0 15 % A
% Cys: 8 0 0 0 0 8 36 0 8 8 0 8 0 0 0 % C
% Asp: 0 0 0 0 15 86 0 0 0 0 0 0 79 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % F
% Gly: 8 0 50 22 8 0 8 0 0 0 36 8 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 22 0 22 0 8 8 0 % I
% Lys: 8 0 0 0 0 0 22 8 8 8 0 8 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 8 43 8 0 0 0 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 8 0 0 8 0 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 8 0 65 0 0 0 0 65 % R
% Ser: 0 29 15 36 0 0 8 50 8 0 8 0 0 0 8 % S
% Thr: 0 58 0 0 0 0 0 8 0 0 8 0 8 8 8 % T
% Val: 43 0 8 0 58 0 0 0 8 0 29 0 8 29 0 % V
% Trp: 0 0 0 0 8 0 0 8 0 0 0 79 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _