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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA4
All Species:
35.15
Human Site:
S294
Identified Species:
51.56
UniProt:
O00629
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00629
NP_002259.1
521
57887
S294
P
H
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Chimpanzee
Pan troglodytes
XP_001158343
497
55292
S294
P
H
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Rhesus Macaque
Macaca mulatta
XP_001097222
521
57902
S294
P
H
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Dog
Lupus familis
XP_534112
497
55001
S270
P
F
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35343
521
57904
S294
P
H
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Rat
Rattus norvegicus
Q56R16
536
60281
M304
R
R
L
V
E
L
L
M
H
N
D
Y
K
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513797
569
62801
S342
P
F
L
V
P
L
L
S
H
Q
E
V
K
V
Q
Chicken
Gallus gallus
Q5ZML1
538
60176
M306
R
R
L
V
E
L
L
M
H
N
D
Y
K
V
V
Frog
Xenopus laevis
P52170
522
57670
Y296
D
R
L
I
Q
L
M
Y
S
P
E
L
S
I
V
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
M304
R
R
L
V
E
L
L
M
H
S
D
Y
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
Q292
P
R
L
V
K
L
L
Q
M
D
E
P
S
I
I
Honey Bee
Apis mellifera
XP_395967
516
57341
S292
P
R
L
I
P
L
L
S
H
K
E
V
K
V
Q
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
G287
T
H
L
V
P
L
L
G
H
V
D
V
K
V
Q
Sea Urchin
Strong. purpuratus
XP_001178060
510
56437
S285
P
T
L
V
P
L
L
S
S
K
E
V
K
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
L294
P
K
L
V
E
L
L
L
H
H
S
P
S
V
L
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
S309
K
R
L
V
E
L
L
S
H
E
S
T
L
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
99.8
82.9
N.A.
98.8
49.2
N.A.
76
47.5
48.4
48.5
N.A.
46.3
70
62
69.6
Protein Similarity:
100
95.3
99.8
88.6
N.A.
99.4
66.7
N.A.
82.4
65
67.4
66.7
N.A.
65.7
82.5
75.8
81.1
P-Site Identity:
100
100
100
93.3
N.A.
100
46.6
N.A.
93.3
46.6
20
46.6
N.A.
40
80
73.3
80
P-Site Similarity:
100
100
100
93.3
N.A.
100
53.3
N.A.
93.3
53.3
46.6
53.3
N.A.
46.6
93.3
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
46.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
61.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
25
0
0
0
0
% D
% Glu:
0
0
0
0
32
0
0
0
0
7
63
0
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
32
0
0
0
0
0
0
82
7
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
0
0
0
0
0
0
0
13
7
% I
% Lys:
7
7
0
0
7
0
0
0
0
13
0
0
75
0
0
% K
% Leu:
0
0
100
0
0
100
94
7
0
0
0
7
7
0
7
% L
% Met:
0
0
0
0
0
0
7
19
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
63
0
0
0
57
0
0
0
0
7
0
13
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
0
38
0
0
0
0
63
% Q
% Arg:
19
44
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
57
13
7
13
0
19
0
0
% S
% Thr:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
88
0
0
0
0
0
7
0
57
0
88
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _