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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA4
All Species:
19.7
Human Site:
S487
Identified Species:
28.89
UniProt:
O00629
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00629
NP_002259.1
521
57887
S487
I
I
D
Q
F
F
S
S
D
D
I
D
E
D
P
Chimpanzee
Pan troglodytes
XP_001158343
497
55292
S463
I
I
D
Q
F
F
S
S
D
D
I
D
E
D
P
Rhesus Macaque
Macaca mulatta
XP_001097222
521
57902
S487
I
I
D
Q
F
F
S
S
D
D
I
D
E
D
P
Dog
Lupus familis
XP_534112
497
55001
G463
I
I
D
Q
Y
F
S
G
D
D
I
D
E
D
P
Cat
Felis silvestris
Mouse
Mus musculus
O35343
521
57904
S487
I
I
D
Q
F
F
S
S
D
D
I
D
E
D
P
Rat
Rattus norvegicus
Q56R16
536
60281
F502
F
D
L
I
E
R
Y
F
G
V
E
E
D
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513797
569
62801
G535
I
I
D
Q
Y
F
S
G
D
D
I
D
E
D
P
Chicken
Gallus gallus
Q5ZML1
538
60176
N489
E
F
L
Q
S
H
E
N
Q
E
I
Y
Q
K
A
Frog
Xenopus laevis
P52170
522
57670
Y488
A
L
A
L
I
E
K
Y
F
S
G
E
E
A
D
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
F502
F
D
L
I
E
H
Y
F
G
V
E
E
E
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
N488
I
I
D
T
Y
F
S
N
G
D
D
E
A
E
Q
Honey Bee
Apis mellifera
XP_395967
516
57341
Y482
A
Y
E
I
I
E
Q
Y
F
S
E
D
T
N
D
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
S480
I
I
D
N
F
F
S
S
D
D
E
T
G
N
V
Sea Urchin
Strong. purpuratus
XP_001178060
510
56437
F476
Y
E
I
I
D
Q
Y
F
S
E
I
D
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
E496
I
L
E
T
Y
W
L
E
E
E
D
D
E
T
Q
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
Y508
A
Y
K
I
I
E
T
Y
F
G
E
E
E
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
99.8
82.9
N.A.
98.8
49.2
N.A.
76
47.5
48.4
48.5
N.A.
46.3
70
62
69.6
Protein Similarity:
100
95.3
99.8
88.6
N.A.
99.4
66.7
N.A.
82.4
65
67.4
66.7
N.A.
65.7
82.5
75.8
81.1
P-Site Identity:
100
100
100
86.6
N.A.
100
13.3
N.A.
86.6
13.3
6.6
13.3
N.A.
40
6.6
60
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
93.3
33.3
20
20
N.A.
66.6
20
66.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
46.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
61.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
0
0
0
0
0
0
0
0
0
7
7
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
50
0
7
0
0
0
44
50
13
57
7
57
19
% D
% Glu:
7
7
13
0
13
19
7
7
7
19
32
32
69
13
0
% E
% Phe:
13
7
0
0
32
50
0
19
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
19
7
7
0
7
0
0
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
57
50
7
32
19
0
0
0
0
0
50
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
7
0
0
0
0
0
0
7
0
% K
% Leu:
0
13
19
7
0
0
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
13
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
44
% P
% Gln:
0
0
0
44
0
7
7
0
7
0
0
0
7
0
13
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
0
50
32
7
13
0
0
0
0
0
% S
% Thr:
0
0
0
13
0
0
7
0
0
0
0
7
7
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
0
0
25
0
19
19
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _