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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFIB All Species: 31.52
Human Site: Y183 Identified Species: 77.04
UniProt: O00712 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00712 NP_005587.2 420 47442 Y183 L D L F L A Y Y V Q E Q D S G
Chimpanzee Pan troglodytes XP_001147769 420 47437 Y183 L D L F L A Y Y V Q E Q D S G
Rhesus Macaque Macaca mulatta XP_001110962 420 47450 Y183 L D L F L A Y Y V Q E Q D S G
Dog Lupus familis XP_864614 415 46856 Y178 L D L F L A Y Y V Q E Q D S G
Cat Felis silvestris
Mouse Mus musculus P97863 570 63488 Y183 L D L F L A Y Y V Q E Q D S G
Rat Rattus norvegicus P09414 509 55958 F182 L D L Y L A Y F V H A A D S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507360 560 62601 Y183 L D L F L A Y Y V Q E Q D S G
Chicken Gallus gallus P17924 560 62604 Y183 L D L F L A Y Y V Q E Q D S G
Frog Xenopus laevis NP_001089172 536 59710 Y228 L D L F L A Y Y V Q D Q D P G
Zebra Danio Brachydanio rerio XP_001921162 553 61079 F206 L D L Y L A Y F V Q E R E A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.7 97.6 N.A. 73.1 55.2 N.A. 73.5 72.8 73.8 49 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 100 98.5 N.A. 73.5 64.8 N.A. 74.1 73.5 75.3 59.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 60 N.A. 100 100 86.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 73.3 N.A. 100 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 100 0 0 0 0 10 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 10 0 90 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 80 0 10 0 10 % E
% Phe: 0 0 0 80 0 0 0 20 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 100 0 100 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 90 0 80 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 80 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 20 0 0 100 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _