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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F3
All Species:
12.12
Human Site:
S267
Identified Species:
26.67
UniProt:
O00716
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00716
NP_001940.1
465
49162
S267
S
K
E
V
T
E
L
S
Q
E
E
K
K
L
D
Chimpanzee
Pan troglodytes
XP_524538
437
47536
K242
F
K
H
L
T
E
D
K
A
N
K
R
L
A
Y
Rhesus Macaque
Macaca mulatta
XP_001103396
425
46803
K231
T
E
L
S
Q
E
E
K
K
L
D
E
L
I
Q
Dog
Lupus familis
XP_545361
509
56204
S311
S
K
E
V
T
E
L
S
Q
E
E
K
K
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O35261
457
48739
S259
S
K
E
V
T
E
L
S
Q
E
E
K
K
L
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
S268
R
R
D
L
S
G
L
S
A
A
E
R
S
L
D
Chicken
Gallus gallus
Q90977
403
43534
R209
Q
T
C
T
V
R
L
R
L
L
T
E
D
P
S
Frog
Xenopus laevis
NP_001090608
426
47125
H232
L
F
K
E
D
E
S
H
D
Y
G
Y
V
T
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
E343
S
L
R
L
E
Q
Q
E
N
E
L
N
K
A
I
Honey Bee
Apis mellifera
XP_396223
416
46049
K222
E
V
A
D
L
E
A
K
E
N
T
L
D
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190160
404
44401
L210
I
H
P
G
D
S
Q
L
S
A
E
T
V
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
75.6
69.5
N.A.
94.1
N.A.
N.A.
45
43.4
39.3
N.A.
N.A.
20.5
30.7
N.A.
41
Protein Similarity:
100
60
79.5
73.8
N.A.
94.8
N.A.
N.A.
55.5
56.9
55.9
N.A.
N.A.
32.6
44.7
N.A.
54.6
P-Site Identity:
100
20
6.6
100
N.A.
100
N.A.
N.A.
33.3
6.6
6.6
N.A.
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
40
46.6
100
N.A.
100
N.A.
N.A.
66.6
13.3
13.3
N.A.
N.A.
33.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
19
19
0
0
0
19
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
10
19
0
10
0
10
0
10
0
19
0
37
% D
% Glu:
10
10
28
10
10
64
10
10
10
37
46
19
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
37
10
0
0
0
0
28
10
0
10
28
37
0
0
% K
% Leu:
10
10
10
28
10
0
46
10
10
19
10
10
19
37
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
19
0
10
0
10
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
0
0
10
10
19
0
28
0
0
0
0
0
10
% Q
% Arg:
10
10
10
0
0
10
0
10
0
0
0
19
0
10
0
% R
% Ser:
37
0
0
10
10
10
10
37
10
0
0
0
10
0
10
% S
% Thr:
10
10
0
10
37
0
0
0
0
0
19
10
0
10
0
% T
% Val:
0
10
0
28
10
0
0
0
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _