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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F3
All Species:
13.94
Human Site:
T169
Identified Species:
30.67
UniProt:
O00716
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00716
NP_001940.1
465
49162
T169
R
S
P
D
S
P
K
T
P
K
S
P
S
E
K
Chimpanzee
Pan troglodytes
XP_524538
437
47536
G151
L
L
S
E
S
E
D
G
V
L
D
L
N
W
A
Rhesus Macaque
Macaca mulatta
XP_001103396
425
46803
D140
P
S
E
K
T
R
Y
D
T
S
L
G
L
L
T
Dog
Lupus familis
XP_545361
509
56204
T213
R
S
P
D
S
P
K
T
P
K
S
P
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
O35261
457
48739
T161
R
S
P
D
S
P
K
T
P
K
S
P
S
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
T170
P
G
L
P
S
P
K
T
P
K
S
P
G
E
K
Chicken
Gallus gallus
Q90977
403
43534
E118
L
T
T
K
R
F
L
E
L
L
S
Q
S
P
D
Frog
Xenopus laevis
NP_001090608
426
47125
G141
L
L
S
Q
S
P
D
G
V
V
D
L
N
W
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
S245
Q
L
A
A
S
V
A
S
S
S
S
S
G
D
R
Honey Bee
Apis mellifera
XP_396223
416
46049
E131
P
T
K
S
K
T
V
E
R
T
R
Y
D
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190160
404
44401
P119
P
S
A
K
T
K
K
P
R
A
P
T
R
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
75.6
69.5
N.A.
94.1
N.A.
N.A.
45
43.4
39.3
N.A.
N.A.
20.5
30.7
N.A.
41
Protein Similarity:
100
60
79.5
73.8
N.A.
94.8
N.A.
N.A.
55.5
56.9
55.9
N.A.
N.A.
32.6
44.7
N.A.
54.6
P-Site Identity:
100
6.6
6.6
100
N.A.
100
N.A.
N.A.
66.6
13.3
13.3
N.A.
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
20
13.3
100
N.A.
100
N.A.
N.A.
66.6
20
20
N.A.
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
10
0
0
10
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
0
0
19
10
0
0
19
0
10
10
10
% D
% Glu:
0
0
10
10
0
10
0
19
0
0
0
0
0
37
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
19
0
0
0
10
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
28
10
10
46
0
0
37
0
0
0
0
37
% K
% Leu:
28
28
10
0
0
0
10
0
10
19
10
19
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% N
% Pro:
37
0
28
10
0
46
0
10
37
0
10
37
0
10
10
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
28
0
0
0
10
10
0
0
19
0
10
0
10
0
10
% R
% Ser:
0
46
19
10
64
0
0
10
10
19
55
10
37
10
10
% S
% Thr:
0
19
10
0
19
10
0
37
10
10
0
10
0
10
10
% T
% Val:
0
0
0
0
0
10
10
0
19
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _