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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: E2F3 All Species: 8.48
Human Site: T363 Identified Species: 18.67
UniProt: O00716 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00716 NP_001940.1 465 49162 T363 E T H S P M K T N N Q D H N G
Chimpanzee Pan troglodytes XP_524538 437 47536 D338 A Q P S S S T D P S I M E P T
Rhesus Macaque Macaca mulatta XP_001103396 425 46803 D327 P M K T N N Q D H N G N I P K
Dog Lupus familis XP_545361 509 56204 T407 E T H S P M K T T N Q D H N G
Cat Felis silvestris
Mouse Mus musculus O35261 457 48739 T355 E T H R P M K T N N Q D H N G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515449 468 50133 H364 G Q Q P A F L H N A G P F N F
Chicken Gallus gallus Q90977 403 43534 R305 S P G S S Q Q R A S P L L H S
Frog Xenopus laevis NP_001090608 426 47125 L328 P I Q P K E E L P A S V P M L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27368 805 87442 G439 E N S P I A P G A G Y V G A P
Honey Bee Apis mellifera XP_396223 416 46049 P318 A V K T S P T P G Y T T T Q P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190160 404 44401 I306 L K S T R G Q I E V Y L C P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.9 75.6 69.5 N.A. 94.1 N.A. N.A. 45 43.4 39.3 N.A. N.A. 20.5 30.7 N.A. 41
Protein Similarity: 100 60 79.5 73.8 N.A. 94.8 N.A. N.A. 55.5 56.9 55.9 N.A. N.A. 32.6 44.7 N.A. 54.6
P-Site Identity: 100 6.6 6.6 93.3 N.A. 93.3 N.A. N.A. 13.3 6.6 0 N.A. N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 13.3 33.3 93.3 N.A. 93.3 N.A. N.A. 13.3 26.6 6.6 N.A. N.A. 6.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 10 10 0 0 19 19 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 19 0 0 0 28 0 0 10 % D
% Glu: 37 0 0 0 0 10 10 0 10 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % F
% Gly: 10 0 10 0 0 10 0 10 10 10 19 0 10 0 28 % G
% His: 0 0 28 0 0 0 0 10 10 0 0 0 28 10 0 % H
% Ile: 0 10 0 0 10 0 0 10 0 0 10 0 10 0 0 % I
% Lys: 0 10 19 0 10 0 28 0 0 0 0 0 0 0 10 % K
% Leu: 10 0 0 0 0 0 10 10 0 0 0 19 10 0 10 % L
% Met: 0 10 0 0 0 28 0 0 0 0 0 10 0 10 0 % M
% Asn: 0 10 0 0 10 10 0 0 28 37 0 10 0 37 0 % N
% Pro: 19 10 10 28 28 10 10 10 19 0 10 10 10 28 19 % P
% Gln: 0 19 19 0 0 10 28 0 0 0 28 0 0 10 0 % Q
% Arg: 0 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 0 19 37 28 10 0 0 0 19 10 0 0 0 10 % S
% Thr: 0 28 0 28 0 0 19 28 10 0 10 10 10 0 10 % T
% Val: 0 10 0 0 0 0 0 0 0 10 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _