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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F3
All Species:
5.76
Human Site:
T62
Identified Species:
12.67
UniProt:
O00716
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00716
NP_001940.1
465
49162
T62
G
A
Y
I
Q
I
L
T
T
N
T
S
T
T
S
Chimpanzee
Pan troglodytes
XP_524538
437
47536
P47
A
T
A
T
Y
Y
T
P
L
Y
P
Q
T
A
P
Rhesus Macaque
Macaca mulatta
XP_001103396
425
46803
T36
D
L
L
T
S
Y
S
T
P
S
A
P
T
S
R
Dog
Lupus familis
XP_545361
509
56204
S63
V
S
R
G
Q
P
V
S
A
S
T
P
Y
I
L
Cat
Felis silvestris
Mouse
Mus musculus
O35261
457
48739
L57
P
G
T
Y
I
Q
I
L
T
T
N
P
S
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
R55
S
A
D
E
P
V
P
R
V
P
G
P
V
G
Q
Chicken
Gallus gallus
Q90977
403
43534
L14
A
A
G
L
A
A
L
L
G
G
A
S
P
H
L
Frog
Xenopus laevis
NP_001090608
426
47125
T37
Q
Q
I
V
I
I
S
T
P
D
V
P
A
E
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
K109
H
V
Y
I
S
L
D
K
G
H
N
T
G
A
V
Honey Bee
Apis mellifera
XP_396223
416
46049
L27
D
M
V
E
T
K
L
L
K
E
E
F
L
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190160
404
44401
T15
T
A
G
R
R
Q
P
T
E
A
K
I
R
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
75.6
69.5
N.A.
94.1
N.A.
N.A.
45
43.4
39.3
N.A.
N.A.
20.5
30.7
N.A.
41
Protein Similarity:
100
60
79.5
73.8
N.A.
94.8
N.A.
N.A.
55.5
56.9
55.9
N.A.
N.A.
32.6
44.7
N.A.
54.6
P-Site Identity:
100
6.6
13.3
13.3
N.A.
13.3
N.A.
N.A.
6.6
20
13.3
N.A.
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
6.6
26.6
40
N.A.
33.3
N.A.
N.A.
13.3
26.6
33.3
N.A.
N.A.
33.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
37
10
0
10
10
0
0
10
10
19
0
10
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
0
0
0
10
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
19
0
0
0
0
10
10
10
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
19
10
0
0
0
0
19
10
10
0
10
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
10
19
19
19
10
0
0
0
0
10
0
10
10
% I
% Lys:
0
0
0
0
0
10
0
10
10
0
10
0
0
0
0
% K
% Leu:
0
10
10
10
0
10
28
28
10
0
0
0
10
0
19
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
0
% N
% Pro:
10
0
0
0
10
10
19
10
19
10
10
46
10
0
10
% P
% Gln:
10
10
0
0
19
19
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
10
10
10
0
0
10
0
0
0
0
10
0
10
% R
% Ser:
10
10
0
0
19
0
19
10
0
19
0
19
10
10
10
% S
% Thr:
10
10
10
19
10
0
10
37
19
10
19
10
28
28
10
% T
% Val:
10
10
10
10
0
10
10
0
10
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
10
10
19
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _