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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F3
All Species:
9.09
Human Site:
Y145
Identified Species:
20
UniProt:
O00716
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00716
NP_001940.1
465
49162
Y145
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
Chimpanzee
Pan troglodytes
XP_524538
437
47536
K127
T
P
K
S
P
G
E
K
T
R
Y
D
T
S
L
Rhesus Macaque
Macaca mulatta
XP_001103396
425
46803
K116
G
L
K
T
P
K
G
K
G
R
A
A
L
R
S
Dog
Lupus familis
XP_545361
509
56204
Y189
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
Cat
Felis silvestris
Mouse
Mus musculus
O35261
457
48739
Y137
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
Q146
L
D
L
E
G
I
G
Q
Q
G
L
P
G
F
R
Chicken
Gallus gallus
Q90977
403
43534
R94
G
R
A
R
I
P
G
R
G
A
K
S
P
G
E
Frog
Xenopus laevis
NP_001090608
426
47125
R117
A
V
K
S
P
G
E
R
S
R
Y
D
T
S
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
V221
D
E
D
V
V
E
R
V
A
K
P
A
S
H
H
Honey Bee
Apis mellifera
XP_396223
416
46049
P107
S
Q
S
A
F
K
A
P
R
G
K
R
R
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190160
404
44401
R95
E
L
D
S
A
G
V
R
P
T
N
I
A
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
75.6
69.5
N.A.
94.1
N.A.
N.A.
45
43.4
39.3
N.A.
N.A.
20.5
30.7
N.A.
41
Protein Similarity:
100
60
79.5
73.8
N.A.
94.8
N.A.
N.A.
55.5
56.9
55.9
N.A.
N.A.
32.6
44.7
N.A.
54.6
P-Site Identity:
100
6.6
6.6
100
N.A.
100
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
20
33.3
100
N.A.
100
N.A.
N.A.
13.3
6.6
20
N.A.
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
0
10
0
10
10
10
19
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
19
0
0
0
0
0
0
0
28
19
0
0
0
% D
% Glu:
10
10
28
10
0
10
19
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
19
28
0
0
37
28
28
0
19
19
0
28
10
10
0
% G
% His:
0
0
0
0
0
28
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
28
0
0
19
0
19
0
10
19
0
0
37
0
% K
% Leu:
37
19
10
0
0
0
0
0
28
0
10
0
37
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
0
0
28
10
0
10
10
0
10
10
10
0
0
% P
% Gln:
0
10
0
0
0
0
28
10
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
10
28
10
28
0
10
10
10
10
% R
% Ser:
10
0
10
55
0
0
0
0
10
28
0
10
10
19
28
% S
% Thr:
10
0
0
10
0
0
0
0
10
10
0
0
19
10
28
% T
% Val:
0
10
0
10
10
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _