KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F3
All Species:
10
Human Site:
Y434
Identified Species:
22
UniProt:
O00716
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00716
NP_001940.1
465
49162
Y434
P
P
L
L
Q
E
D
Y
L
L
S
L
G
E
E
Chimpanzee
Pan troglodytes
XP_524538
437
47536
S406
P
L
I
S
F
S
P
S
L
D
Q
D
D
Y
L
Rhesus Macaque
Macaca mulatta
XP_001103396
425
46803
L395
P
L
L
Q
E
D
Y
L
L
S
L
G
E
E
E
Dog
Lupus familis
XP_545361
509
56204
Y478
P
P
L
L
Q
E
D
Y
L
L
S
L
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
O35261
457
48739
Y426
P
P
L
L
Q
E
D
Y
L
L
S
L
G
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
Q437
P
M
T
G
F
S
P
Q
L
D
H
D
D
Y
L
Chicken
Gallus gallus
Q90977
403
43534
Q373
F
I
A
L
S
P
P
Q
P
Q
D
Y
H
F
G
Frog
Xenopus laevis
NP_001090608
426
47125
Q396
S
L
S
P
T
S
S
Q
E
Y
S
F
G
L
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
H521
D
I
A
M
G
Q
H
H
N
L
N
Q
Q
Q
Q
Honey Bee
Apis mellifera
XP_396223
416
46049
E386
M
R
D
A
L
L
C
E
S
D
D
Y
G
P
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190160
404
44401
V374
N
G
L
D
D
D
F
V
A
L
S
P
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
75.6
69.5
N.A.
94.1
N.A.
N.A.
45
43.4
39.3
N.A.
N.A.
20.5
30.7
N.A.
41
Protein Similarity:
100
60
79.5
73.8
N.A.
94.8
N.A.
N.A.
55.5
56.9
55.9
N.A.
N.A.
32.6
44.7
N.A.
54.6
P-Site Identity:
100
13.3
33.3
100
N.A.
100
N.A.
N.A.
13.3
6.6
13.3
N.A.
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
20
46.6
100
N.A.
100
N.A.
N.A.
13.3
6.6
20
N.A.
N.A.
46.6
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
10
19
28
0
0
28
19
19
19
0
0
% D
% Glu:
0
0
0
0
10
28
0
10
10
0
0
0
10
37
37
% E
% Phe:
10
0
0
0
19
0
10
0
0
0
0
10
0
10
0
% F
% Gly:
0
10
0
10
10
0
0
0
0
0
0
10
46
0
10
% G
% His:
0
0
0
0
0
0
10
10
0
0
10
0
10
0
0
% H
% Ile:
0
19
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
28
46
37
10
10
0
10
55
46
10
28
0
10
19
% L
% Met:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% N
% Pro:
55
28
0
10
0
10
28
0
10
0
0
10
10
10
0
% P
% Gln:
0
0
0
10
28
10
0
28
0
10
10
10
10
10
19
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
10
28
10
10
10
10
46
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
28
0
10
0
19
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _