Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP6C All Species: 0
Human Site: S116 Identified Species: 0
UniProt: O00743 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00743 NP_001116827.1 305 35144 S116 L L R G N H E S R Q I T Q V Y
Chimpanzee Pan troglodytes XP_001139308 412 47020
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536672 387 43961
Cat Felis silvestris
Mouse Mus musculus Q9CQR6 305 35141
Rat Rattus norvegicus Q5BJ92 307 35049
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073233 305 35140
Frog Xenopus laevis Q6IP91 307 35104
Zebra Danio Brachydanio rerio A9JRC7 307 35078
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27884 303 34740
Honey Bee Apis mellifera XP_394400 303 34880
Nematode Worm Caenorhab. elegans Q9XW79 333 37341
Sea Urchin Strong. purpuratus XP_001185396 248 28554
Poplar Tree Populus trichocarpa XP_002310919 303 34851
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SX52 303 34801
Baker's Yeast Sacchar. cerevisiae P20604 311 35519
Red Bread Mold Neurospora crassa P48580 327 37273
Conservation
Percent
Protein Identity: 100 62.1 N.A. 78 N.A. 99.6 61.2 N.A. N.A. 99.6 61.8 61.5 N.A. 74.7 81.3 55.2 71.4
Protein Similarity: 100 65.5 N.A. 78 N.A. 99.6 77.5 N.A. N.A. 100 77.5 77.5 N.A. 87.8 90.8 70.8 77
P-Site Identity: 100 0 N.A. 0 N.A. 0 0 N.A. N.A. 0 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 0 N.A. 0 N.A. 0 0 N.A. N.A. 0 0 0 N.A. 0 0 0 0
Percent
Protein Identity: 69.1 N.A. N.A. 69.1 61.7 55.6
Protein Similarity: 84.2 N.A. N.A. 83.6 76.2 69.1
P-Site Identity: 0 N.A. N.A. 0 0 0
P-Site Similarity: 0 N.A. N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 100 0 0 100 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 100 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _