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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP6C
All Species:
43.64
Human Site:
Y123
Identified Species:
64
UniProt:
O00743
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00743
NP_001116827.1
305
35144
Y123
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
Q
Chimpanzee
Pan troglodytes
XP_001139308
412
47020
Y230
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536672
387
43961
Y205
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQR6
305
35141
Y123
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
Q
Rat
Rattus norvegicus
Q5BJ92
307
35049
Y124
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073233
305
35140
Y123
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
Q
Frog
Xenopus laevis
Q6IP91
307
35104
Y124
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
L
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
Y124
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27884
303
34740
G122
R
Q
I
T
K
V
Y
G
F
F
D
E
C
F
S
Honey Bee
Apis mellifera
XP_394400
303
34880
F123
Q
I
T
H
V
Y
G
F
Y
D
E
C
Q
N
K
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
Y149
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
L
Sea Urchin
Strong. purpuratus
XP_001185396
248
28554
A81
T
K
Y
G
N
A
N
A
W
R
Y
C
T
K
V
Poplar Tree
Populus trichocarpa
XP_002310919
303
34851
F122
Q
L
T
Q
V
Y
G
F
Y
D
E
C
Q
R
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX52
303
34801
F122
Q
L
T
Q
V
Y
G
F
Y
D
E
C
Q
R
K
Baker's Yeast
Sacchar. cerevisiae
P20604
311
35519
Y124
S
R
Q
I
T
Q
V
Y
G
F
Y
E
E
C
L
Red Bread Mold
Neurospora crassa
P48580
327
37273
Y145
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
C
L
Conservation
Percent
Protein Identity:
100
62.1
N.A.
78
N.A.
99.6
61.2
N.A.
N.A.
99.6
61.8
61.5
N.A.
74.7
81.3
55.2
71.4
Protein Similarity:
100
65.5
N.A.
78
N.A.
99.6
77.5
N.A.
N.A.
100
77.5
77.5
N.A.
87.8
90.8
70.8
77
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
100
93.3
93.3
N.A.
6.6
0
93.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
100
93.3
93.3
N.A.
20
20
93.3
20
Percent
Protein Identity:
69.1
N.A.
N.A.
69.1
61.7
55.6
Protein Similarity:
84.2
N.A.
N.A.
83.6
76.2
69.1
P-Site Identity:
0
N.A.
N.A.
0
86.6
93.3
P-Site Similarity:
20
N.A.
N.A.
20
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
7
69
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
19
7
63
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
19
13
69
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
7
75
0
0
0
7
0
% F
% Gly:
0
0
0
7
0
0
19
7
69
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
69
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
7
0
0
0
0
0
0
0
0
7
19
% K
% Leu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
7
69
13
0
69
0
0
0
0
0
0
19
0
32
% Q
% Arg:
7
69
0
0
0
0
0
0
0
7
0
0
0
13
0
% R
% Ser:
69
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% S
% Thr:
7
0
19
7
69
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
19
7
69
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
19
7
69
19
0
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _