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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP6C
All Species:
40
Human Site:
Y244
Identified Species:
58.67
UniProt:
O00743
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00743
NP_001116827.1
305
35144
Y244
H
Q
L
V
H
E
G
Y
K
F
M
F
D
E
K
Chimpanzee
Pan troglodytes
XP_001139308
412
47020
Y351
H
Q
L
V
H
E
G
Y
K
F
M
F
D
E
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536672
387
43961
Y326
H
Q
Q
V
H
E
G
Y
K
F
M
F
D
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQR6
305
35141
Y244
H
Q
L
V
H
E
G
Y
K
F
M
F
D
E
K
Rat
Rattus norvegicus
Q5BJ92
307
35049
Y245
H
Q
L
V
M
E
G
Y
K
W
H
F
N
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073233
305
35140
Y244
H
Q
L
V
H
E
G
Y
K
F
M
F
D
E
K
Frog
Xenopus laevis
Q6IP91
307
35104
Y245
H
Q
L
V
M
E
G
Y
K
W
H
F
N
E
T
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
Y245
H
Q
L
V
M
E
G
Y
K
W
H
F
N
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27884
303
34740
I242
H
Q
L
V
N
E
G
I
K
Y
M
F
D
G
K
Honey Bee
Apis mellifera
XP_394400
303
34880
Y242
H
Q
L
V
H
E
G
Y
R
Y
M
F
N
D
K
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
Y271
H
Q
L
V
M
E
G
Y
K
W
H
F
N
E
K
Sea Urchin
Strong. purpuratus
XP_001185396
248
28554
K188
Q
L
V
Q
E
G
Y
K
Y
M
F
D
D
K
L
Poplar Tree
Populus trichocarpa
XP_002310919
303
34851
K242
Q
L
V
Q
E
G
L
K
Y
M
F
Q
D
K
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX52
303
34801
K242
Q
L
V
Q
E
G
L
K
Y
M
F
Q
D
K
G
Baker's Yeast
Sacchar. cerevisiae
P20604
311
35519
K246
Q
L
V
M
E
G
F
K
Y
H
F
P
E
K
D
Red Bread Mold
Neurospora crassa
P48580
327
37273
Y266
H
Q
L
V
M
E
G
Y
N
W
S
Q
D
R
N
Conservation
Percent
Protein Identity:
100
62.1
N.A.
78
N.A.
99.6
61.2
N.A.
N.A.
99.6
61.8
61.5
N.A.
74.7
81.3
55.2
71.4
Protein Similarity:
100
65.5
N.A.
78
N.A.
99.6
77.5
N.A.
N.A.
100
77.5
77.5
N.A.
87.8
90.8
70.8
77
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
66.6
N.A.
N.A.
100
66.6
66.6
N.A.
73.3
73.3
73.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
80
N.A.
N.A.
100
80
80
N.A.
86.6
100
86.6
20
Percent
Protein Identity:
69.1
N.A.
N.A.
69.1
61.7
55.6
Protein Similarity:
84.2
N.A.
N.A.
83.6
76.2
69.1
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
53.3
P-Site Similarity:
20
N.A.
N.A.
20
26.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
63
7
7
% D
% Glu:
0
0
0
0
25
75
0
0
0
0
0
0
7
57
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
32
25
69
0
0
0
% F
% Gly:
0
0
0
0
0
25
75
0
0
0
0
0
0
7
13
% G
% His:
75
0
0
0
38
0
0
0
0
7
25
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
25
63
0
0
0
0
25
50
% K
% Leu:
0
25
69
0
0
0
13
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
7
32
0
0
0
0
19
44
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
0
0
0
32
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
25
75
7
19
0
0
0
0
0
0
0
19
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% T
% Val:
0
0
25
75
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
32
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
69
25
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _