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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT10B
All Species:
17.88
Human Site:
S216
Identified Species:
35.76
UniProt:
O00744
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00744
NP_003385.2
389
43000
S216
F
S
R
D
F
L
D
S
R
E
A
P
R
D
I
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
Q204
A
V
K
R
F
L
K
Q
E
C
K
C
H
G
V
Rhesus Macaque
Macaca mulatta
XP_001104947
389
42934
S216
F
S
R
D
F
L
D
S
R
E
A
P
R
D
I
Dog
Lupus familis
XP_543687
389
42951
S216
F
S
R
D
F
L
D
S
R
E
A
P
R
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P48614
389
43100
S216
F
S
R
D
F
L
D
S
R
E
A
P
R
D
I
Rat
Rattus norvegicus
Q9QXQ5
351
39025
L199
E
A
G
R
K
A
I
L
T
H
M
R
V
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
Q205
A
V
K
R
F
L
K
Q
E
C
K
C
H
G
V
Chicken
Gallus gallus
P49337
351
38945
L199
E
A
G
R
K
A
I
L
N
N
M
R
V
E
C
Frog
Xenopus laevis
P31285
352
39697
H200
T
S
I
L
D
H
R
H
L
K
C
K
C
H
G
Zebra Danio
Brachydanio rerio
Q801F7
427
47389
S242
F
S
R
D
W
L
D
S
R
G
S
P
R
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396944
378
42015
C223
G
S
C
E
L
K
T
C
W
K
V
A
P
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781564
350
39795
H199
A
E
K
R
C
K
C
H
G
M
S
G
S
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
98.7
97.6
N.A.
96.9
39.3
N.A.
37.5
38
36.7
61.5
N.A.
N.A.
45.7
N.A.
44.4
Protein Similarity:
100
52.7
98.9
98.9
N.A.
97.9
54.5
N.A.
52.4
54.2
51.6
72.8
N.A.
N.A.
62.9
N.A.
59.6
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
13.3
0
6.6
80
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
13.3
N.A.
26.6
13.3
13.3
93.3
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
17
0
0
0
17
0
0
0
0
34
9
0
0
0
% A
% Cys:
0
0
9
0
9
0
9
9
0
17
9
17
9
9
17
% C
% Asp:
0
0
0
42
9
0
42
0
0
0
0
0
0
50
0
% D
% Glu:
17
9
0
9
0
0
0
0
17
34
0
0
0
17
0
% E
% Phe:
42
0
0
0
50
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
17
0
0
0
0
0
9
9
0
9
0
17
9
% G
% His:
0
0
0
0
0
9
0
17
0
9
0
0
17
9
0
% H
% Ile:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
42
% I
% Lys:
0
0
25
0
17
17
17
0
0
17
17
9
0
0
0
% K
% Leu:
0
0
0
9
9
59
0
17
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
42
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
9
% Q
% Arg:
0
0
42
42
0
0
9
0
42
0
0
17
42
0
0
% R
% Ser:
0
59
0
0
0
0
0
42
0
0
17
0
9
0
0
% S
% Thr:
9
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
0
9
0
17
0
17
% V
% Trp:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _