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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME4
All Species:
21.82
Human Site:
S155
Identified Species:
40
UniProt:
O00746
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00746
NP_005000.1
187
20659
S155
N
V
I
H
A
S
D
S
V
E
G
A
Q
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085126
187
20710
S155
N
V
I
H
A
S
D
S
V
E
G
A
Q
R
E
Dog
Lupus familis
XP_534114
773
84104
S741
N
I
I
H
A
S
D
S
V
E
G
A
R
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV84
186
20530
S154
N
V
I
H
A
S
D
S
V
D
G
A
Q
R
E
Rat
Rattus norvegicus
Q05982
152
17174
D121
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515701
267
30034
N95
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
Chicken
Gallus gallus
O57535
153
17269
D122
R
N
I
I
H
G
S
D
S
V
E
S
A
Q
K
Frog
Xenopus laevis
P70010
154
17471
S123
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
Zebra Danio
Brachydanio rerio
XP_002661154
193
21501
S162
N
V
V
H
A
S
D
S
V
E
G
A
Q
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08879
153
17151
D122
R
N
I
I
H
G
S
D
A
V
E
S
A
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64903
231
25532
V152
E
Y
I
T
S
G
P
V
V
C
M
A
W
E
G
Baker's Yeast
Sacchar. cerevisiae
P36010
153
17148
D122
R
N
V
C
H
G
S
D
S
V
D
S
A
E
R
Red Bread Mold
Neurospora crassa
Q9UUY8
152
16882
D121
R
N
V
C
H
G
S
D
S
V
E
N
A
K
K
Conservation
Percent
Protein Identity:
100
N.A.
97.3
20.9
N.A.
82.3
47.5
N.A.
39.7
46.5
45.9
61.1
N.A.
44.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.8
22.2
N.A.
87.6
63
N.A.
52
62.5
61.5
74.6
N.A.
59.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
6.6
N.A.
6.6
6.6
66.6
93.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
33.3
26.6
80
100
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
41.7
43.3
Protein Similarity:
N.A.
N.A.
N.A.
51.9
58.8
57.7
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
39
0
0
0
8
8
0
54
39
0
0
% A
% Cys:
0
0
0
16
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
47
39
0
8
16
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
39
31
0
0
31
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
47
0
0
0
0
39
0
0
0
16
% G
% His:
0
0
0
47
39
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
70
24
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
31
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
47
39
0
0
0
0
0
8
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
31
8
0
% Q
% Arg:
47
0
0
0
0
0
0
0
0
0
0
0
8
39
8
% R
% Ser:
0
0
0
0
8
47
39
47
31
0
8
39
0
0
0
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
39
24
0
0
0
0
8
54
39
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _