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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME4
All Species:
7.27
Human Site:
S23
Identified Species:
13.33
UniProt:
O00746
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00746
NP_005000.1
187
20659
S23
G
P
R
A
P
G
P
S
L
L
V
R
H
G
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085126
187
20710
S23
G
P
R
A
P
D
P
S
L
L
V
R
P
S
S
Dog
Lupus familis
XP_534114
773
84104
S609
G
P
W
A
P
G
P
S
L
L
A
H
P
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV84
186
20530
L24
G
P
R
F
Q
C
L
L
V
R
P
S
S
G
G
Rat
Rattus norvegicus
Q05982
152
17174
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515701
267
30034
W78
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
Chicken
Gallus gallus
O57535
153
17269
Frog
Xenopus laevis
P70010
154
17471
Zebra Danio
Brachydanio rerio
XP_002661154
193
21501
A30
S
R
A
L
G
I
G
A
A
R
S
L
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08879
153
17151
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64903
231
25532
S23
A
S
P
P
E
R
N
S
A
S
L
N
P
H
C
Baker's Yeast
Sacchar. cerevisiae
P36010
153
17148
Red Bread Mold
Neurospora crassa
Q9UUY8
152
16882
Conservation
Percent
Protein Identity:
100
N.A.
97.3
20.9
N.A.
82.3
47.5
N.A.
39.7
46.5
45.9
61.1
N.A.
44.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.8
22.2
N.A.
87.6
63
N.A.
52
62.5
61.5
74.6
N.A.
59.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
80
66.6
N.A.
26.6
0
N.A.
13.3
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
80
66.6
N.A.
33.3
0
N.A.
20
0
0
6.6
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
41.7
43.3
Protein Similarity:
N.A.
N.A.
N.A.
51.9
58.8
57.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
24
8
0
0
8
16
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
39
0
0
0
8
16
8
0
0
8
0
0
0
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
0
0
8
8
24
24
16
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
16
0
8
0
% N
% Pro:
0
39
8
8
24
0
24
0
0
0
8
0
24
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
24
0
0
8
0
0
0
16
0
16
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
31
0
8
8
8
16
16
24
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
8
0
8
0
16
0
8
8
0
% V
% Trp:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _