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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME4
All Species:
20
Human Site:
Y94
Identified Species:
36.67
UniProt:
O00746
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00746
NP_005000.1
187
20659
Y94
D
L
R
R
K
P
F
Y
P
A
L
I
R
Y
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085126
187
20710
Y94
D
L
R
R
K
P
F
Y
P
A
L
I
R
Y
M
Dog
Lupus familis
XP_534114
773
84104
Y680
D
L
Q
R
K
P
F
Y
P
P
L
I
S
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV84
186
20530
Y93
D
L
Q
R
K
P
F
Y
P
A
L
I
S
Y
M
Rat
Rattus norvegicus
Q05982
152
17174
F60
I
D
L
K
D
R
P
F
F
S
G
L
V
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515701
267
30034
R149
R
F
E
Q
K
G
F
R
L
V
A
M
K
M
L
Chicken
Gallus gallus
O57535
153
17269
F61
I
D
L
K
D
R
P
F
Y
P
G
L
V
K
Y
Frog
Xenopus laevis
P70010
154
17471
Y62
D
L
K
D
R
P
F
Y
P
G
L
V
E
Y
M
Zebra Danio
Brachydanio rerio
XP_002661154
193
21501
Y101
S
L
Q
K
K
P
F
Y
S
S
L
L
Y
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08879
153
17151
F61
A
D
L
S
A
R
P
F
F
P
G
L
V
N
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64903
231
25532
K91
E
E
T
Y
I
M
V
K
P
D
G
I
Q
R
G
Baker's Yeast
Sacchar. cerevisiae
P36010
153
17148
F61
A
E
H
V
G
K
P
F
F
P
K
M
V
S
F
Red Bread Mold
Neurospora crassa
Q9UUY8
152
16882
F60
E
D
L
N
T
K
P
F
F
A
G
L
I
K
Y
Conservation
Percent
Protein Identity:
100
N.A.
97.3
20.9
N.A.
82.3
47.5
N.A.
39.7
46.5
45.9
61.1
N.A.
44.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.8
22.2
N.A.
87.6
63
N.A.
52
62.5
61.5
74.6
N.A.
59.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
80
N.A.
86.6
0
N.A.
13.3
0
60
53.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
26.6
N.A.
40
20
80
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
41.7
43.3
Protein Similarity:
N.A.
N.A.
N.A.
51.9
58.8
57.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
0
0
0
0
31
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
31
0
8
16
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
16
16
8
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
54
39
31
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
8
0
0
0
8
39
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
0
0
0
0
0
0
39
8
0
0
% I
% Lys:
0
0
8
24
47
16
0
8
0
0
8
0
8
24
0
% K
% Leu:
0
47
31
0
0
0
0
0
8
0
47
39
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
16
0
8
47
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
47
39
0
47
31
0
0
0
0
0
% P
% Gln:
0
0
24
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
16
31
8
24
0
8
0
0
0
0
16
8
0
% R
% Ser:
8
0
0
8
0
0
0
0
8
16
0
0
16
8
0
% S
% Thr:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
8
0
8
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
47
8
0
0
0
8
47
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _