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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT7A
All Species:
13.03
Human Site:
S259
Identified Species:
26.06
UniProt:
O00755
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00755
NP_004616.2
349
39005
S259
L
K
I
K
K
P
L
S
Y
R
K
P
M
D
T
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
R259
G
F
T
V
A
N
E
R
F
K
K
P
T
K
N
Rhesus Macaque
Macaca mulatta
XP_001110372
349
39282
S259
L
R
I
K
Q
L
R
S
Y
Q
K
P
M
E
T
Dog
Lupus familis
XP_849210
350
39005
S260
L
K
I
K
K
P
L
S
Y
R
K
P
M
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P24383
349
38970
S259
L
K
I
K
K
P
L
S
Y
R
K
P
M
D
T
Rat
Rattus norvegicus
Q9QXQ5
351
39025
Q261
A
L
V
P
R
N
A
Q
F
K
P
H
T
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
R260
G
F
T
V
A
N
K
R
F
K
K
P
T
K
N
Chicken
Gallus gallus
P49337
351
38945
Q261
V
L
V
P
K
N
S
Q
F
K
P
H
T
D
E
Frog
Xenopus laevis
P49338
351
39148
Q261
V
L
V
P
K
N
S
Q
F
K
P
H
T
D
E
Zebra Danio
Brachydanio rerio
P47793
352
39413
F262
L
V
P
R
N
S
Q
F
K
P
H
T
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28465
352
39744
V262
T
A
R
A
Q
K
P
V
L
D
W
P
K
R
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787051
370
41758
N280
L
K
V
K
D
S
E
N
Y
R
K
P
R
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
77.9
98.5
N.A.
98.8
46.4
N.A.
45.9
46.1
45.8
48.2
N.A.
48.8
N.A.
N.A.
57.5
Protein Similarity:
100
60
91.4
99.4
N.A.
99.1
64.9
N.A.
61.7
63.8
64
65.6
N.A.
65
N.A.
N.A.
73.7
P-Site Identity:
100
13.3
60
100
N.A.
100
6.6
N.A.
13.3
13.3
13.3
6.6
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
26.6
86.6
100
N.A.
100
33.3
N.A.
26.6
40
40
20
N.A.
13.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
17
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
9
0
0
9
50
9
% D
% Glu:
0
0
0
0
0
0
17
0
0
0
0
0
0
17
25
% E
% Phe:
0
17
0
0
0
0
0
9
42
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
25
0
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
34
0
42
42
9
9
0
9
42
59
0
9
17
0
% K
% Leu:
50
25
0
0
0
9
25
0
9
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
9
% M
% Asn:
0
0
0
0
9
42
0
9
0
0
0
0
0
0
17
% N
% Pro:
0
0
9
25
0
25
9
0
0
9
25
67
0
0
0
% P
% Gln:
0
0
0
0
17
0
9
25
0
9
0
0
0
0
0
% Q
% Arg:
0
9
9
9
9
0
9
17
0
34
0
0
9
9
0
% R
% Ser:
0
0
0
0
0
17
17
34
0
0
0
0
0
0
9
% S
% Thr:
9
0
17
0
0
0
0
0
0
0
0
9
42
0
34
% T
% Val:
17
9
34
17
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _