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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT7A
All Species:
13.64
Human Site:
S54
Identified Species:
27.27
UniProt:
O00755
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00755
NP_004616.2
349
39005
S54
R
Q
R
A
I
C
Q
S
R
P
D
A
I
I
V
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
R57
S
Q
R
Q
L
C
H
R
H
P
D
V
M
R
A
Rhesus Macaque
Macaca mulatta
XP_001110372
349
39282
S54
R
Q
R
A
I
C
Q
S
R
P
D
A
I
I
V
Dog
Lupus familis
XP_849210
350
39005
S54
R
Q
R
A
I
C
Q
S
R
P
D
A
I
I
V
Cat
Felis silvestris
Mouse
Mus musculus
P24383
349
38970
S54
R
Q
R
A
I
C
Q
S
R
P
D
A
I
I
V
Rat
Rattus norvegicus
Q9QXQ5
351
39025
R59
R
Q
V
Q
M
C
K
R
N
L
E
V
M
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
R58
R
Q
R
Q
L
C
H
R
H
P
E
V
M
R
S
Chicken
Gallus gallus
P49337
351
38945
R59
R
Q
V
Q
M
C
K
R
N
L
E
V
M
D
S
Frog
Xenopus laevis
P49338
351
39148
R59
R
Q
V
Q
M
C
K
R
N
L
E
V
M
D
S
Zebra Danio
Brachydanio rerio
P47793
352
39413
R59
R
Q
V
Q
I
C
K
R
N
V
E
V
M
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28465
352
39744
E46
G
Q
R
N
M
C
R
E
M
P
D
A
L
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787051
370
41758
R75
R
Q
R
A
I
C
Q
R
R
P
D
A
I
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
77.9
98.5
N.A.
98.8
46.4
N.A.
45.9
46.1
45.8
48.2
N.A.
48.8
N.A.
N.A.
57.5
Protein Similarity:
100
60
91.4
99.4
N.A.
99.1
64.9
N.A.
61.7
63.8
64
65.6
N.A.
65
N.A.
N.A.
73.7
P-Site Identity:
100
33.3
100
100
N.A.
100
20
N.A.
33.3
20
20
26.6
N.A.
46.6
N.A.
N.A.
80
P-Site Similarity:
100
46.6
100
100
N.A.
100
46.6
N.A.
53.3
46.6
46.6
46.6
N.A.
66.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
0
0
0
0
0
0
0
50
0
0
34
% A
% Cys:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
59
0
0
34
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
42
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
17
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
0
0
0
42
42
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
0
0
0
0
25
0
0
9
0
0
% L
% Met:
0
0
0
0
34
0
0
0
9
0
0
0
50
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
34
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% P
% Gln:
0
100
0
50
0
0
42
0
0
0
0
0
0
0
0
% Q
% Arg:
84
0
67
0
0
0
9
59
42
0
0
0
0
17
0
% R
% Ser:
9
0
0
0
0
0
0
34
0
0
0
0
0
0
34
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
34
0
0
0
0
0
0
9
0
50
0
9
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _