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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT7A
All Species:
9.09
Human Site:
Y226
Identified Species:
18.18
UniProt:
O00755
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00755
NP_004616.2
349
39005
Y226
P
Q
F
R
E
L
G
Y
V
L
K
D
K
Y
N
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
D226
T
C
W
L
A
M
A
D
F
R
K
T
G
D
Y
Rhesus Macaque
Macaca mulatta
XP_001110372
349
39282
H226
P
K
F
R
E
V
G
H
L
L
K
E
K
Y
N
Dog
Lupus familis
XP_849210
350
39005
Y227
P
Q
F
R
E
L
G
Y
V
L
K
D
K
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
P24383
349
38970
Y226
P
Q
F
R
E
L
G
Y
V
L
K
D
K
Y
N
Rat
Rattus norvegicus
Q9QXQ5
351
39025
R228
W
R
A
V
P
P
F
R
Q
V
G
H
A
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
D227
T
C
W
L
A
M
A
D
F
R
K
T
G
D
Y
Chicken
Gallus gallus
P49337
351
38945
R228
W
K
A
M
P
P
F
R
K
V
G
N
V
L
K
Frog
Xenopus laevis
P49338
351
39148
R228
W
K
A
M
P
T
F
R
K
V
G
N
V
L
K
Zebra Danio
Brachydanio rerio
P47793
352
39413
K229
K
A
M
P
P
F
R
K
V
G
N
V
I
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28465
352
39744
Q229
D
R
L
M
L
K
Y
Q
K
A
K
T
V
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787051
370
41758
D247
P
N
F
R
S
V
G
D
V
L
K
E
K
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
77.9
98.5
N.A.
98.8
46.4
N.A.
45.9
46.1
45.8
48.2
N.A.
48.8
N.A.
N.A.
57.5
Protein Similarity:
100
60
91.4
99.4
N.A.
99.1
64.9
N.A.
61.7
63.8
64
65.6
N.A.
65
N.A.
N.A.
73.7
P-Site Identity:
100
6.6
66.6
100
N.A.
100
0
N.A.
6.6
0
0
6.6
N.A.
6.6
N.A.
N.A.
60
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
20
20
20
6.6
N.A.
13.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
0
17
0
17
0
0
9
0
0
9
0
9
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
25
0
0
0
25
0
17
0
% D
% Glu:
0
0
0
0
34
0
0
0
0
0
0
17
0
0
17
% E
% Phe:
0
0
42
0
0
9
25
0
17
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
42
0
0
9
25
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
25
0
0
0
9
0
9
25
0
67
0
42
9
25
% K
% Leu:
0
0
9
17
9
25
0
0
9
42
0
0
0
25
0
% L
% Met:
0
0
9
25
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
9
17
0
0
34
% N
% Pro:
42
0
0
9
34
17
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
0
0
0
0
9
9
0
0
0
0
9
0
% Q
% Arg:
0
17
0
42
0
0
9
25
0
17
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
17
0
0
0
0
9
0
0
0
0
0
25
0
0
0
% T
% Val:
0
0
0
9
0
17
0
0
42
25
0
9
25
0
0
% V
% Trp:
25
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
25
0
0
0
0
0
42
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _