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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACACB
All Species:
3.94
Human Site:
S174
Identified Species:
8.67
UniProt:
O00763
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00763
NP_001084.3
2458
276555
S174
L
G
S
F
D
D
Y
S
S
D
E
D
S
V
A
Chimpanzee
Pan troglodytes
XP_511428
2532
285118
S220
D
N
S
E
D
E
I
S
N
L
V
K
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001111672
2327
263361
H174
E
Y
I
K
M
A
D
H
Y
V
P
V
P
G
G
Dog
Lupus familis
XP_867594
2323
262742
H174
E
Y
I
K
M
A
D
H
Y
V
P
V
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWU9
2345
265238
Y174
Y
I
K
M
A
D
H
Y
V
P
V
P
G
G
P
Rat
Rattus norvegicus
P11497
2345
265175
Y174
Y
I
K
M
A
D
H
Y
V
P
V
P
G
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508230
2450
275669
K176
E
A
V
A
G
A
F
K
A
S
S
R
R
S
S
Chicken
Gallus gallus
P11029
2324
262701
H174
E
Y
I
K
M
A
D
H
Y
V
P
V
P
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684081
2240
253300
Q173
V
A
S
S
I
V
A
Q
S
A
G
I
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097227
2571
287535
R210
L
K
M
Q
N
D
V
R
Q
N
G
D
I
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00955
2233
250335
S166
L
P
E
K
L
S
Q
S
K
R
K
V
I
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
72.3
72.2
N.A.
72.1
72.1
N.A.
83.8
71.8
N.A.
71.7
N.A.
56.3
N.A.
N.A.
N.A.
Protein Similarity:
100
81.9
82.9
82.7
N.A.
82.8
82.8
N.A.
91.7
83
N.A.
81.5
N.A.
71.8
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
0
N.A.
6.6
13.3
N.A.
0
0
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
0
0
N.A.
13.3
20
N.A.
20
0
N.A.
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
10
19
37
10
0
10
10
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
19
37
28
0
0
10
0
19
0
10
0
% D
% Glu:
37
0
10
10
0
10
0
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
19
0
19
46
28
% G
% His:
0
0
0
0
0
0
19
28
0
0
0
0
0
0
0
% H
% Ile:
0
19
28
0
10
0
10
0
0
0
0
10
19
0
10
% I
% Lys:
0
10
19
37
0
0
0
10
10
0
10
10
0
0
0
% K
% Leu:
28
0
0
0
10
0
0
0
0
10
0
0
10
0
19
% L
% Met:
0
0
10
19
28
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
19
28
19
37
0
10
% P
% Gln:
0
0
0
10
0
0
10
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
10
10
0
0
% R
% Ser:
0
0
28
10
0
10
0
28
19
10
10
0
10
19
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
10
0
10
0
0
10
10
0
19
28
28
37
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
28
0
0
0
0
10
19
28
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _