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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACACB All Species: 23.94
Human Site: S2019 Identified Species: 52.67
UniProt: O00763 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00763 NP_001084.3 2458 276555 S2019 Y M P K D N H S P V P I I T P
Chimpanzee Pan troglodytes XP_511428 2532 285118 S2094 Y M P K S V H S S V P L L N S
Rhesus Macaque Macaca mulatta XP_001111672 2327 263361 S1889 Y M P K S V H S S V P L L N S
Dog Lupus familis XP_867594 2323 262742 S1885 Y M P K N V R S L V P L L N S
Cat Felis silvestris
Mouse Mus musculus Q5SWU9 2345 265238 S1907 Y M P K S V H S S V P L L N S
Rat Rattus norvegicus P11497 2345 265175 S1907 Y M P K N V H S S V P L L N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508230 2450 275669 S2011 Y M P K D N R S P V P I I T P
Chicken Gallus gallus P11029 2324 262701 S1885 Y M P K S V Y S P V P I L K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684081 2240 253300 T1838 L C G R P H P T V K G A W Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097227 2571 287535 C2128 Y I P A Y I G C D L P I V L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00955 2233 250335 V1831 K D T W D R P V D F T P T N D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 72.3 72.2 N.A. 72.1 72.1 N.A. 83.8 71.8 N.A. 71.7 N.A. 56.3 N.A. N.A. N.A.
Protein Similarity: 100 81.9 82.9 82.7 N.A. 82.8 82.8 N.A. 91.7 83 N.A. 81.5 N.A. 71.8 N.A. N.A. N.A.
P-Site Identity: 100 53.3 53.3 46.6 N.A. 53.3 53.3 N.A. 93.3 60 N.A. 0 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 66.6 66.6 N.A. 66.6 73.3 N.A. 93.3 73.3 N.A. 20 N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 59.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 28 0 0 0 19 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 10 46 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 0 0 0 37 19 0 0 % I
% Lys: 10 0 0 73 0 0 0 0 0 10 0 0 0 10 0 % K
% Leu: 10 0 0 0 0 0 0 0 10 10 0 46 55 10 0 % L
% Met: 0 73 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 19 0 0 0 0 0 0 0 55 0 % N
% Pro: 0 0 82 0 10 0 19 0 28 0 82 10 0 0 28 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 10 0 10 19 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 37 0 0 73 37 0 0 0 0 0 55 % S
% Thr: 0 0 10 0 0 0 0 10 0 0 10 0 10 19 0 % T
% Val: 0 0 0 0 0 55 0 10 10 73 0 0 10 0 10 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 82 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _